A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms.

A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms.

Electron microscopy (EM) achieves the highest spatial resolution in protein localization, but specific protein EM labeling has lacked generally applicable genetically encoded tags for in situ visualization in cells and tissues. Here we introduce "miniSOG" (for mini Singlet Oxygen Generator...

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Bibliographic Details
Main Authors: Xiaokun Shu, Varda Lev-Ram, Thomas J Deerinck, Yingchuan Qi, Ericka B Ramko, Michael W Davidson, Yishi Jin, Mark H Ellisman, Roger Y Tsien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3071375?pdf=render

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