Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a clinical syndrome associated with mitochondrial disorders (MIDs). This report illustrates a case of MELAS syndrome with hypothyroidism and psychiatric disorders, which is different from the common clinical...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-03-01
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| Series: | eNeurologicalSci |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650216300375 |
| _version_ | 1819076902958137344 |
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| author | Yu-Xing Ge Bo Shang Wen-Zhen Chen You Lu Jue Wang |
| author_facet | Yu-Xing Ge Bo Shang Wen-Zhen Chen You Lu Jue Wang |
| author_sort | Yu-Xing Ge |
| collection | DOAJ |
| description | Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a clinical syndrome associated with mitochondrial disorders (MIDs). This report illustrates a case of MELAS syndrome with hypothyroidism and psychiatric disorders, which is different from the common clinical manifestations of MELAS syndrome, such as exercise intolerance, migraine-like headaches, hearing loss and seizures etc. There are considerable interests in the possibility that mitochondrial dysfunction may play a role in the pathogenesis of endocrine dysfunctions and psychiatric disorders in MELAS syndrome. |
| first_indexed | 2024-12-21T18:48:41Z |
| format | Article |
| id | doaj.art-fa329371307e40bba27e08c9f45d73c9 |
| institution | Directory Open Access Journal |
| issn | 2405-6502 |
| language | English |
| last_indexed | 2024-12-21T18:48:41Z |
| publishDate | 2017-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj.art-fa329371307e40bba27e08c9f45d73c92022-12-21T18:53:49ZengElseviereNeurologicalSci2405-65022017-03-016C162010.1016/j.ensci.2016.11.005Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disordersYu-Xing GeBo ShangWen-Zhen ChenYou LuJue WangMitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a clinical syndrome associated with mitochondrial disorders (MIDs). This report illustrates a case of MELAS syndrome with hypothyroidism and psychiatric disorders, which is different from the common clinical manifestations of MELAS syndrome, such as exercise intolerance, migraine-like headaches, hearing loss and seizures etc. There are considerable interests in the possibility that mitochondrial dysfunction may play a role in the pathogenesis of endocrine dysfunctions and psychiatric disorders in MELAS syndrome.http://www.sciencedirect.com/science/article/pii/S2405650216300375MELASMitochondrial disordersEndocrine dysfunctionPsychiatric disorders |
| spellingShingle | Yu-Xing Ge Bo Shang Wen-Zhen Chen You Lu Jue Wang Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders eNeurologicalSci MELAS Mitochondrial disorders Endocrine dysfunction Psychiatric disorders |
| title | Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders |
| title_full | Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders |
| title_fullStr | Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders |
| title_full_unstemmed | Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders |
| title_short | Adult-onset of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome with hypothyroidism and psychiatric disorders |
| title_sort | adult onset of mitochondrial myopathy encephalopathy lactic acidosis and stroke like episodes melas syndrome with hypothyroidism and psychiatric disorders |
| topic | MELAS Mitochondrial disorders Endocrine dysfunction Psychiatric disorders |
| url | http://www.sciencedirect.com/science/article/pii/S2405650216300375 |
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