Development of a pseudovirus-based assay for measuring neutralizing antibodies against Coxsackievirus A10

Development of a pseudovirus-based assay for measuring neutralizing antibodies against Coxsackievirus A10

Coxsackievirus A10 (CV-A10) has recently emerged as a major pathogen of hand, foot, and mouth disease in children worldwide. Currently no effective treatments are available; development of anti-CV-A10 vaccine is a most cost-effective way for CV-A10 prevention. Robust assay to measure neutralizing an...

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Bibliographic Details
Main Authors: Kelei Li, Fangyu Dong, Bopei Cui, Lisha Cui, Pei Liu, Chao Ma, Haifa Zheng, Xing Wu, Zhenglun Liang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-06-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
hfmd
coxsackievirus a10
neutralizing antibody
pseudovirus
cytopathic effect
Online Access:http://dx.doi.org/10.1080/21645515.2019.1691404

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