High-throughput screening and validation of antibodies against synaptic proteins to explore opioid signaling dynamics
Lemos Duarte et al. describe a strategy to produce, validate, and utilize highly-specific recombinant antibodies. As a proof of principle, they demonstrate development and validation of a panel of antibodies against proteins relevant to signaling by opiates. Their antibody-based tool can be useful i...
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Bibliographic Details
| Main Authors: |
Mariana Lemos Duarte,
Nikita A. Trimbake,
Achla Gupta,
Christine Tumanut,
Xiaomin Fan,
Catherine Woods,
Akila Ram,
Ivone Gomes,
Erin N. Bobeck,
Deborah Schechtman,
Lakshmi A. Devi |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-02-01
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| Series: | Communications Biology
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| Online Access: | https://doi.org/10.1038/s42003-021-01744-8
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