Therapeutic implications of transcriptomics in head and neck cancer patient-derived xenografts.

There are currently no clinical strategies utilizing tumor gene expression to inform therapeutic selection for patients with head and neck squamous cell carcinoma (HNSCC). One of the challenges in developing predictive biomarkers is the limited characterization of preclinical HNSCC models. Patient-d...

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Bibliographic Details
Main Authors: Rex H Lee, Ritu Roy, Hua Li, Aaron Hechmer, Tian Ran Zhu, Adila Izgutdina, Adam B Olshen, Daniel E Johnson, Jennifer R Grandis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0282177