Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features

Background: Insomnia is highly prevalent in patients with substance use disorders (SUD), and it has been related to a worse course of addiction. Insomnia during detoxification in a hospital has not been adequately studied. This study aims to compare sociodemographic, clinical, and psychopathological...

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Main Authors: Lara Grau-López, Laia Grau-López, Constanza Daigre, Raúl Felipe Palma-Álvarez, Nieves Martínez-Luna, Elena Ros-Cucurull, Jose Antonio Ramos-Quiroga, Carlos Roncero
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2020.540022/full
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author Lara Grau-López
Lara Grau-López
Lara Grau-López
Lara Grau-López
Laia Grau-López
Constanza Daigre
Constanza Daigre
Constanza Daigre
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Nieves Martínez-Luna
Nieves Martínez-Luna
Nieves Martínez-Luna
Nieves Martínez-Luna
Elena Ros-Cucurull
Elena Ros-Cucurull
Elena Ros-Cucurull
Elena Ros-Cucurull
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Carlos Roncero
Carlos Roncero
author_facet Lara Grau-López
Lara Grau-López
Lara Grau-López
Lara Grau-López
Laia Grau-López
Constanza Daigre
Constanza Daigre
Constanza Daigre
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Nieves Martínez-Luna
Nieves Martínez-Luna
Nieves Martínez-Luna
Nieves Martínez-Luna
Elena Ros-Cucurull
Elena Ros-Cucurull
Elena Ros-Cucurull
Elena Ros-Cucurull
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Carlos Roncero
Carlos Roncero
author_sort Lara Grau-López
collection DOAJ
description Background: Insomnia is highly prevalent in patients with substance use disorders (SUD), and it has been related to a worse course of addiction. Insomnia during detoxification in a hospital has not been adequately studied. This study aims to compare sociodemographic, clinical, and psychopathological characteristics of SUD patients undergoing a detoxification program, by comorbidity and insomnia symptoms.Methodology: We recruited 481 patients who received pharmacological and psychotherapeutic treatment for detoxification. They were evaluated through semi-structured interviews, standardized questionnaires, and a specific sleep log. A bivariate and multivariate analysis of the data was performed.Results: Insomnia was reported by 66.5% patients, with sleep-maintenance insomnia the most frequent issue, followed by early morning awakening and sleep-onset insomnia. Patients with alcohol use disorder and cannabis use disorder had higher prevalence of sleep-onset insomnia. Patients with cocaine and heroin use disorder had higher prevalence of sleep-maintenance insomnia. Independent factors that allowed the identification of insomnia symptoms included being female (OR: 3.43), polysubstance use (OR: 2.85), comorbid anxiety disorder (OR: 2.02), and prior admission for detoxification (OR: 1.22).Conclusions: Insomnia symptoms are very prevalent in patients admitted for detoxification. The diagnosis and therapeutic strategies for the insomnia symptoms should be improved, especially in women and in patients with greater addiction severity and with anxiety disorders.
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spelling doaj.art-fa3b18c60a5842fab8528b2fe94e0bb22022-12-22T00:28:18ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-11-011110.3389/fpsyt.2020.540022540022Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical FeaturesLara Grau-López0Lara Grau-López1Lara Grau-López2Lara Grau-López3Laia Grau-López4Constanza Daigre5Constanza Daigre6Constanza Daigre7Raúl Felipe Palma-Álvarez8Raúl Felipe Palma-Álvarez9Raúl Felipe Palma-Álvarez10Raúl Felipe Palma-Álvarez11Nieves Martínez-Luna12Nieves Martínez-Luna13Nieves Martínez-Luna14Nieves Martínez-Luna15Elena Ros-Cucurull16Elena Ros-Cucurull17Elena Ros-Cucurull18Elena Ros-Cucurull19Jose Antonio Ramos-Quiroga20Jose Antonio Ramos-Quiroga21Jose Antonio Ramos-Quiroga22Jose Antonio Ramos-Quiroga23Carlos Roncero24Carlos Roncero25Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, SpainDepartment of Neurosciences, Hospital Universitari Germans Trias i Pujol, Badalona, SpainGroup of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, SpainDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, SpainDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, SpainDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, SpainDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, SpainPsychiatric Service, University of Salamanca Health Care Complex, Institute of Biomedicine of Salamanca, University of Salamanca, Salamanca, SpainPsychiatric Unit, School of Medicine University of Salamanca, Salamanca, SpainBackground: Insomnia is highly prevalent in patients with substance use disorders (SUD), and it has been related to a worse course of addiction. Insomnia during detoxification in a hospital has not been adequately studied. This study aims to compare sociodemographic, clinical, and psychopathological characteristics of SUD patients undergoing a detoxification program, by comorbidity and insomnia symptoms.Methodology: We recruited 481 patients who received pharmacological and psychotherapeutic treatment for detoxification. They were evaluated through semi-structured interviews, standardized questionnaires, and a specific sleep log. A bivariate and multivariate analysis of the data was performed.Results: Insomnia was reported by 66.5% patients, with sleep-maintenance insomnia the most frequent issue, followed by early morning awakening and sleep-onset insomnia. Patients with alcohol use disorder and cannabis use disorder had higher prevalence of sleep-onset insomnia. Patients with cocaine and heroin use disorder had higher prevalence of sleep-maintenance insomnia. Independent factors that allowed the identification of insomnia symptoms included being female (OR: 3.43), polysubstance use (OR: 2.85), comorbid anxiety disorder (OR: 2.02), and prior admission for detoxification (OR: 1.22).Conclusions: Insomnia symptoms are very prevalent in patients admitted for detoxification. The diagnosis and therapeutic strategies for the insomnia symptoms should be improved, especially in women and in patients with greater addiction severity and with anxiety disorders.https://www.frontiersin.org/articles/10.3389/fpsyt.2020.540022/fulladdictioninsomniasleep disorderswomendetoxification processanxiety disorders
spellingShingle Lara Grau-López
Lara Grau-López
Lara Grau-López
Lara Grau-López
Laia Grau-López
Constanza Daigre
Constanza Daigre
Constanza Daigre
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Raúl Felipe Palma-Álvarez
Nieves Martínez-Luna
Nieves Martínez-Luna
Nieves Martínez-Luna
Nieves Martínez-Luna
Elena Ros-Cucurull
Elena Ros-Cucurull
Elena Ros-Cucurull
Elena Ros-Cucurull
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Jose Antonio Ramos-Quiroga
Carlos Roncero
Carlos Roncero
Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features
Frontiers in Psychiatry
addiction
insomnia
sleep disorders
women
detoxification process
anxiety disorders
title Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features
title_full Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features
title_fullStr Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features
title_full_unstemmed Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features
title_short Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features
title_sort insomnia symptoms in patients with substance use disorders during detoxification and associated clinical features
topic addiction
insomnia
sleep disorders
women
detoxification process
anxiety disorders
url https://www.frontiersin.org/articles/10.3389/fpsyt.2020.540022/full
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