A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
Abstract Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a styl...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-37253-3 |
| _version_ | 1797795686785220608 |
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| author | Eriku Yamada Koji Fujita Takuro Watanabe Takafumi Koyama Takuya Ibara Akiko Yamamoto Kazuya Tsukamoto Hidetoshi Kaburagi Akimoto Nimura Toshitaka Yoshii Yuta Sugiura Atsushi Okawa |
| author_facet | Eriku Yamada Koji Fujita Takuro Watanabe Takafumi Koyama Takuya Ibara Akiko Yamamoto Kazuya Tsukamoto Hidetoshi Kaburagi Akimoto Nimura Toshitaka Yoshii Yuta Sugiura Atsushi Okawa |
| author_sort | Eriku Yamada |
| collection | DOAJ |
| description | Abstract Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, the participants traced three different shapes displayed on a tablet device. During the tasks, writing behaviors, such as the coordinates, velocity, and pressure of the stylus tip, along with the drawing time, were recorded. From these data, features related to the drawing pressure, and time to trace each shape and combination of shapes were used as training data for the support vector machine, a machine learning algorithm. To evaluate the accuracy, a receiver operating characteristic curve was generated, and the area under the curve (AUC) was calculated. Models with triangular waveforms tended to be the most accurate. The best triangular wave model identified patients with and without CM with 76% sensitivity and 76% specificity, yielding an AUC of 0.80. Our model was able to classify CM with high accuracy and could be applied to the development of disease screening systems useful outside the hospital setting. |
| first_indexed | 2024-03-13T03:21:46Z |
| format | Article |
| id | doaj.art-fa3b5d5e08be4cd5aa36a4541e7579eb |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-13T03:21:46Z |
| publishDate | 2023-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-fa3b5d5e08be4cd5aa36a4541e7579eb2023-06-25T11:18:02ZengNature PortfolioScientific Reports2045-23222023-06-011311810.1038/s41598-023-37253-3A screening method for cervical myelopathy using machine learning to analyze a drawing behaviorEriku Yamada0Koji Fujita1Takuro Watanabe2Takafumi Koyama3Takuya Ibara4Akiko Yamamoto5Kazuya Tsukamoto6Hidetoshi Kaburagi7Akimoto Nimura8Toshitaka Yoshii9Yuta Sugiura10Atsushi Okawa11Department of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Functional Joint Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)School of Science for Open and Environmental Systems, Graduate School of Science and Technology, Keio UniversityDepartment of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Functional Joint Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Functional Joint Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Department of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)School of Science for Open and Environmental Systems, Graduate School of Science and Technology, Keio UniversityDepartment of Orthopedic and Spinal Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)Abstract Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, the participants traced three different shapes displayed on a tablet device. During the tasks, writing behaviors, such as the coordinates, velocity, and pressure of the stylus tip, along with the drawing time, were recorded. From these data, features related to the drawing pressure, and time to trace each shape and combination of shapes were used as training data for the support vector machine, a machine learning algorithm. To evaluate the accuracy, a receiver operating characteristic curve was generated, and the area under the curve (AUC) was calculated. Models with triangular waveforms tended to be the most accurate. The best triangular wave model identified patients with and without CM with 76% sensitivity and 76% specificity, yielding an AUC of 0.80. Our model was able to classify CM with high accuracy and could be applied to the development of disease screening systems useful outside the hospital setting.https://doi.org/10.1038/s41598-023-37253-3 |
| spellingShingle | Eriku Yamada Koji Fujita Takuro Watanabe Takafumi Koyama Takuya Ibara Akiko Yamamoto Kazuya Tsukamoto Hidetoshi Kaburagi Akimoto Nimura Toshitaka Yoshii Yuta Sugiura Atsushi Okawa A screening method for cervical myelopathy using machine learning to analyze a drawing behavior Scientific Reports |
| title | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
| title_full | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
| title_fullStr | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
| title_full_unstemmed | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
| title_short | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
| title_sort | screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
| url | https://doi.org/10.1038/s41598-023-37253-3 |
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