Ablation of the deubiquitinase USP15 ameliorates nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Ablation of the deubiquitinase USP15 ameliorates nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Abstract Nonalcoholic fatty liver disease (NAFLD) occurs due to the accumulation of fat in the liver, leading to fatal liver diseases such as nonalcoholic steatohepatitis (NASH) and cirrhosis. Elucidation of the molecular mechanisms underlying NAFLD is critical for its prevention and therapy. Here,...

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Main Authors: Jung-Hwan Baek, Myung Sup Kim, Hye Ryeon Jung, Min-Seon Hwang, Chan-ho Lee, Dai Hoon Han, Yong-ho Lee, Eugene C. Yi, Seung-Soon Im, Ilseon Hwang, Kyungeun Kim, Joon-Yong Chung, Kyung-Hee Chun
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01036-7

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