Investigation of the Antitumor Activity and Toxicity of Tumor-Derived Exosomes Fused with Long-Circulating and pH-Sensitive Liposomes Containing Doxorubicin

Investigation of the Antitumor Activity and Toxicity of Tumor-Derived Exosomes Fused with Long-Circulating and pH-Sensitive Liposomes Containing Doxorubicin

Exosome–liposome hybrid nanocarriers containing chemotherapeutic agents have been developed to enhance drug delivery, improve the efficacy of the treatment of metastatic cancer, and overcome chemoresistance in cancer therapy. Thus, the objectives of this study were to investigate the toxicological p...

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Bibliographic Details
Main Authors: Eliza Rocha Gomes, Fernanda Rezende Souza, Geovanni Dantas Cassali, Adriano de Paula Sabino, André Luis Branco de Barros, Mônica Cristina Oliveira
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceutics
Subjects:
acute toxicity
breast cancer
metastasis
exosomes
liposomes
doxorubicin
Online Access:https://www.mdpi.com/1999-4923/14/11/2256

Internet

https://www.mdpi.com/1999-4923/14/11/2256

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