Functional Characterization of the Internal Symmetry of MRAP2 Antiparallel Homodimer

Functional Characterization of the Internal Symmetry of MRAP2 Antiparallel Homodimer

The melanocortin receptors are defined as a series of vital pharmaceutical targets to regulate neuronal appetite and maintain controllable body weight for mammals and teleosts. Melanocortin receptor accessory protein 2 (MRAP2) functions as an essential accessory player that modulates the surface tra...

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Bibliographic Details
Main Authors: Meng Wang, Linyu Pi, Xiaowei Lei, Lei Li, Jing Xu, Zhe Kuang, Cong Zhang, Liang Li, Chao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Endocrinology
Subjects:
MRAP2
GPCR
dimerization
internal symmetry
MC4R
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.750797/full

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