Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat
Objective: Citrullus lanatus is an antioxidant and it has been shown to reduce oxidative stress. Previous study confirmed antioxidants have essential effect on infertility by their role on reactive oxygen’s spaces. Materials and Methods: Wistar male rat (n = 20) were allocated into two g...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Aras Part Medical International Press
2014-01-01
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| Series: | Crescent Journal of Medical and Biological Sciences |
| Subjects: | |
| Online Access: | http://cjmb.org/PDF/CJMB-1-25.pdf |
| _version_ | 1818393027855515648 |
|---|---|
| author | Khaki Arash Fathiazad Fatemeh Nouri Mohammad Khaki Amir Afshin |
| author_facet | Khaki Arash Fathiazad Fatemeh Nouri Mohammad Khaki Amir Afshin |
| author_sort | Khaki Arash |
| collection | DOAJ |
| description | Objective: Citrullus lanatus is an antioxidant and it has been shown to reduce oxidative stress. Previous
study confirmed antioxidants have essential effect on infertility by their role on reactive oxygen’s spaces.
Materials and Methods: Wistar male rat (n = 20) were allocated into two groups, control group (n = 10)
and C. lanatus group that received 30 mg/kg, (n = 10), by gavage method, daily for, 4 weeks, respectively;
however, the control group just received an equal volume of distilled water daily. Animals were kept in
standard condition. In 28 day, for measurement blood glucose and testosterone, 5 cc blood of each rat
were collected then prepared for analysis.
Results: Serum testosterone significantly was increased in group that has received 30 mg/kg of extract,
(P < 0.05) in comparison to control group (P < 0.05). Blood glucose was decreased in extract group but was
not significantly when compared to control group (P > 0.05).
Conclusion: Since in our study 30 mg/kg C. lanatus has significantly increased serum testosterone and
hence it seem this results can beneficial effects on fertility and need more evaluations in next researches. |
| first_indexed | 2024-12-14T05:38:47Z |
| format | Article |
| id | doaj.art-fa491987fc7d4255831e92f1edf47c21 |
| institution | Directory Open Access Journal |
| issn | 2148-9696 |
| language | English |
| last_indexed | 2024-12-14T05:38:47Z |
| publishDate | 2014-01-01 |
| publisher | Aras Part Medical International Press |
| record_format | Article |
| series | Crescent Journal of Medical and Biological Sciences |
| spelling | doaj.art-fa491987fc7d4255831e92f1edf47c212022-12-21T23:15:05ZengAras Part Medical International PressCrescent Journal of Medical and Biological Sciences2148-96962014-01-01112527CJMB_20150712122022Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in RatKhaki Arash0Fathiazad Fatemeh1Nouri Mohammad2Khaki Amir Afshin3Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Pharmacognosy, Tabriz University of Medical Sciences, Tabriz, IranWomen’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, IranWomen’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, IranObjective: Citrullus lanatus is an antioxidant and it has been shown to reduce oxidative stress. Previous study confirmed antioxidants have essential effect on infertility by their role on reactive oxygen’s spaces. Materials and Methods: Wistar male rat (n = 20) were allocated into two groups, control group (n = 10) and C. lanatus group that received 30 mg/kg, (n = 10), by gavage method, daily for, 4 weeks, respectively; however, the control group just received an equal volume of distilled water daily. Animals were kept in standard condition. In 28 day, for measurement blood glucose and testosterone, 5 cc blood of each rat were collected then prepared for analysis. Results: Serum testosterone significantly was increased in group that has received 30 mg/kg of extract, (P < 0.05) in comparison to control group (P < 0.05). Blood glucose was decreased in extract group but was not significantly when compared to control group (P > 0.05). Conclusion: Since in our study 30 mg/kg C. lanatus has significantly increased serum testosterone and hence it seem this results can beneficial effects on fertility and need more evaluations in next researches.http://cjmb.org/PDF/CJMB-1-25.pdfCitrullus lanatusRatTestosterone |
| spellingShingle | Khaki Arash Fathiazad Fatemeh Nouri Mohammad Khaki Amir Afshin Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat Crescent Journal of Medical and Biological Sciences Citrullus lanatus Rat Testosterone |
| title | Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat |
| title_full | Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat |
| title_fullStr | Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat |
| title_full_unstemmed | Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat |
| title_short | Effect of Citrullus lanatus Seeds Extracts on Serum Total Testosterone in Rat |
| title_sort | effect of citrullus lanatus seeds extracts on serum total testosterone in rat |
| topic | Citrullus lanatus Rat Testosterone |
| url | http://cjmb.org/PDF/CJMB-1-25.pdf |
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