Proteomics Reveals the Potential Protective Mechanism of Hydrogen Sulfide on Retinal Ganglion Cells in an Ischemia/Reperfusion Injury Animal Model

Proteomics Reveals the Potential Protective Mechanism of Hydrogen Sulfide on Retinal Ganglion Cells in an Ischemia/Reperfusion Injury Animal Model

Glaucoma is the leading cause of irreversible blindness and is characterized by progressive retinal ganglion cell (RGC) degeneration. Hydrogen sulfide (H<sub>2</sub>S) is a potent neurotransmitter and has been proven to protect RGCs against glaucomatous injury in vitro and in vivo. This...

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Bibliographic Details
Main Authors: Hanhan Liu, Natarajan Perumal, Caroline Manicam, Karl Mercieca, Verena Prokosch
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceuticals
Subjects:
hydrogen sulfide
glaucoma
neuronal apoptosis
label-free mass spectrometry
mitochondrial function
signalling pathways
Online Access:https://www.mdpi.com/1424-8247/13/9/213

Internet

https://www.mdpi.com/1424-8247/13/9/213

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