Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma
BackgroundEnergy-based devices (EBD) have been popularized in thyroidectomy worldwide. Microdissection tungsten needle (MDTN) is characterized by the ultra-sharp tip providing safe and meticulous dissection with effective hemostasis. However, little study has applied MDTN in thyroidectomy.MethodsThi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.896275/full |
| _version_ | 1817997908728872960 |
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| author | Weijie Zheng Shan Zhu Yimin Zhang Zhong Wang Shichong Liao Shengrong Sun |
| author_facet | Weijie Zheng Shan Zhu Yimin Zhang Zhong Wang Shichong Liao Shengrong Sun |
| author_sort | Weijie Zheng |
| collection | DOAJ |
| description | BackgroundEnergy-based devices (EBD) have been popularized in thyroidectomy worldwide. Microdissection tungsten needle (MDTN) is characterized by the ultra-sharp tip providing safe and meticulous dissection with effective hemostasis. However, little study has applied MDTN in thyroidectomy.MethodsThis retrospective study compared clinical data of the patients who underwent total thyroidectomy (TT) with central neck dissection (CND) using MDTN, harmonic scalpel (HS), and conventional electrocautery (CE). We assessed outcomes related to surgical efficacy and safety. The injury degree of tissue was assessed by biochemical indicators and early-stage inflammatory factors in the drainage fluid. Histological sections of the thyroid specimens were evaluated to compare levels of thermal damage by the three EBD.ResultsThere was a significant decrease in the intraoperative blood loss, operation time and 24-hour drainage volume in the MDTN group compared to the CE group. The total drainage volume, duration of drainage, and average length of stay of the MDTN group were less compared to the CE group though they did not reach statistical significance. No disparity was observed between the MDTN group and HS group in these variables. Total costs were not significantly different among these groups. The incidence of recurrent laryngeal nerve (RLN) injury was the lowest using MDTN compared to the CE (P = 0.034) and HS (not significant). No statistical differences were observed among these groups regarding postoperative wound pain and infection, hypoparathyroidism, and postoperative hemorrhage. Analysis of biochemical indicators showed a lower level of hemoglobin in the MDTN and HS group than the CE group (P = 0.046 and 0.038, respectively) and less triglyceride in the HS group than the MDTN and CE group (P = 0.002 and 0.029, respectively) but no significant difference in cholesterol level in these groups. Early-stage inflammatory factors including TNF-α and IL-6 showed significantly higher concentration in the CE group than the MDTN and HS group. Histological sections of thyroid specimens revealed that MDTN caused the lowest degree of thermal damage followed by HS then CE.
ConclusionMDTN exhibited comparable surgical efficacy and safety outcomes as HS in thyroidectomy. Therefore, MDTN is a safe and viable alternative for hemostasis in thyroidectomy. |
| first_indexed | 2024-04-14T02:45:15Z |
| format | Article |
| id | doaj.art-fa498d4c73f9431aa79f343d7fa84278 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-14T02:45:15Z |
| publishDate | 2022-08-01 |
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| series | Frontiers in Surgery |
| spelling | doaj.art-fa498d4c73f9431aa79f343d7fa842782022-12-22T02:16:37ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-08-01910.3389/fsurg.2022.896275896275Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinomaWeijie ZhengShan ZhuYimin ZhangZhong WangShichong LiaoShengrong SunBackgroundEnergy-based devices (EBD) have been popularized in thyroidectomy worldwide. Microdissection tungsten needle (MDTN) is characterized by the ultra-sharp tip providing safe and meticulous dissection with effective hemostasis. However, little study has applied MDTN in thyroidectomy.MethodsThis retrospective study compared clinical data of the patients who underwent total thyroidectomy (TT) with central neck dissection (CND) using MDTN, harmonic scalpel (HS), and conventional electrocautery (CE). We assessed outcomes related to surgical efficacy and safety. The injury degree of tissue was assessed by biochemical indicators and early-stage inflammatory factors in the drainage fluid. Histological sections of the thyroid specimens were evaluated to compare levels of thermal damage by the three EBD.ResultsThere was a significant decrease in the intraoperative blood loss, operation time and 24-hour drainage volume in the MDTN group compared to the CE group. The total drainage volume, duration of drainage, and average length of stay of the MDTN group were less compared to the CE group though they did not reach statistical significance. No disparity was observed between the MDTN group and HS group in these variables. Total costs were not significantly different among these groups. The incidence of recurrent laryngeal nerve (RLN) injury was the lowest using MDTN compared to the CE (P = 0.034) and HS (not significant). No statistical differences were observed among these groups regarding postoperative wound pain and infection, hypoparathyroidism, and postoperative hemorrhage. Analysis of biochemical indicators showed a lower level of hemoglobin in the MDTN and HS group than the CE group (P = 0.046 and 0.038, respectively) and less triglyceride in the HS group than the MDTN and CE group (P = 0.002 and 0.029, respectively) but no significant difference in cholesterol level in these groups. Early-stage inflammatory factors including TNF-α and IL-6 showed significantly higher concentration in the CE group than the MDTN and HS group. Histological sections of thyroid specimens revealed that MDTN caused the lowest degree of thermal damage followed by HS then CE. ConclusionMDTN exhibited comparable surgical efficacy and safety outcomes as HS in thyroidectomy. Therefore, MDTN is a safe and viable alternative for hemostasis in thyroidectomy.https://www.frontiersin.org/articles/10.3389/fsurg.2022.896275/fullmicrodissection tungsten needleharmonic scalpelenergy-based devicestotal thyroidectomycentral neck dissectionpapillary thyroid carcinoma |
| spellingShingle | Weijie Zheng Shan Zhu Yimin Zhang Zhong Wang Shichong Liao Shengrong Sun Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma Frontiers in Surgery microdissection tungsten needle harmonic scalpel energy-based devices total thyroidectomy central neck dissection papillary thyroid carcinoma |
| title | Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma |
| title_full | Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma |
| title_fullStr | Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma |
| title_full_unstemmed | Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma |
| title_short | Novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma |
| title_sort | novel application of microdissection tungsten needle in total thyroidectomy with central neck dissection for papillary thyroid carcinoma |
| topic | microdissection tungsten needle harmonic scalpel energy-based devices total thyroidectomy central neck dissection papillary thyroid carcinoma |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.896275/full |
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