GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins
GPIHBP1, a small glycosylphosphatidylinositol-anchored glycoprotein, is required for the lipolytic processing of triglyceride-rich lipoproteins. GPIHBP1 knockout mice exhibit chylomicronemia, even on a low-fat diet, with plasma triglyceride levels of 3,500–5,000 mg/dl. GPIHBP1 is expressed highly in...
Main Authors: | Anne P. Beigneux, Brandon S.J. Davies, André Bensadoun, Loren G. Fong, Stephen G. Young |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2009-01-01
|
Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520305873 |
Similar Items
-
Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL[S]
by: Mikael Larsson, et al.
Published: (2017-09-01) -
Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure
by: Mikael Larsson, et al.
Published: (2018-04-01) -
A novel NanoBiT-based assay monitors the interaction between lipoprotein lipase and GPIHBP1 in real time[S]
by: Shwetha K. Shetty, et al.
Published: (2020-04-01) -
Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL
by: Xuchen Hu, et al.
Published: (2017-01-01) -
GPIHBP1, an endothelial cell transporter for lipoprotein lipase
by: Stephen G. Young, et al.
Published: (2011-11-01)