Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation

Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation

Long-term potentiation (LTP) is a molecular basis of memory formation. Here, we demonstrate that LTP critically depends on fructose 1,6-bisphosphatase 2 (Fbp2)—a glyconeogenic enzyme and moonlighting protein protecting mitochondria against stress. We show that LTP induction regulates Fbp2 associatio...

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Bibliographic Details
Main Authors: Przemysław Duda, Tomasz Wójtowicz, Jakub Janczara, Daniel Krowarsch, Aleksandra Czyrek, Agnieszka Gizak, Dariusz Rakus
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
memory formation
moonlighting protein
protein–protein interaction
astrocyte-neuron lactate shuttle
Online Access:https://www.mdpi.com/2073-4409/9/6/1375

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