Association of the bovine growth hormone gene with Holstein cattle reproductive parameters
ABSTRACT Objective. To determine the association of intron 3 polymorphism of the bovine growth hormone (BGH) gene, with age at first service, first birth, first postpartum service and second birth in a population of Holstein cows in the state of Antioquia. Materials and methods. The study was condu...
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| Format: | Article |
| Language: | English |
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Universidad de Cordoba
2014-09-01
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| Series: | Revista MVZ Cordoba |
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| Online Access: | http://revistas.unicordoba.edu.co/index.php/revistamvz/article/view/87 |
| _version_ | 1819121532377497600 |
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| author | Juliana Arango G Julián Echeverri Z Albeiro López H |
| author_facet | Juliana Arango G Julián Echeverri Z Albeiro López H |
| author_sort | Juliana Arango G |
| collection | DOAJ |
| description | ABSTRACT
Objective. To determine the association of intron 3 polymorphism of the bovine growth hormone (BGH) gene, with age at first service, first birth, first postpartum service and second birth in a population of Holstein cows in the state of Antioquia. Materials and methods. The study was conducted on 408 Holstein cows in 8 herds. Genotyping was performed using PCR-RFLP technique with DNA extracted from peripheral blood by the salting out technique. The Phenotypic information used was collected for 4 years, from a dairy production control program. To determine the association between characteristics and gene polymorphism, parametric statistical analyzes were performed as generalized linear models and linear regression analysis. Results. Allele frequency (positive) was 0.91 and was 0.09 for (negative) allele. Genotypic frequencies were 0.77, 0.2 and 0.03 for (positive/positive), (positive/negative) and (negative/negative) respectively. There were significant differences between the mean of age at first service, age at first birth, age at first postpartum service and age at second birth. For all of the (negative/negative) genotype characteristics there were greater ages for each event. Conclusions. These results suggest that intron-3 polymorphism of the BGH gene is associated with reproductive traits, facilitating the selection of individuals with favorable genotypes for use in breeding programs. |
| first_indexed | 2024-12-22T06:38:03Z |
| format | Article |
| id | doaj.art-fa4d016a1309452095b4a77b60d62a54 |
| institution | Directory Open Access Journal |
| issn | 0122-0268 1909-0544 |
| language | English |
| last_indexed | 2024-12-22T06:38:03Z |
| publishDate | 2014-09-01 |
| publisher | Universidad de Cordoba |
| record_format | Article |
| series | Revista MVZ Cordoba |
| spelling | doaj.art-fa4d016a1309452095b4a77b60d62a542022-12-21T18:35:32ZengUniversidad de CordobaRevista MVZ Cordoba0122-02681909-05442014-09-0119310.21897/rmvz.87Association of the bovine growth hormone gene with Holstein cattle reproductive parametersJuliana Arango G0Julián Echeverri Z1Albeiro López H2Universidad Nacional de Colombia, Facultad de Ciencias Agropecuarias, Departamento de Producción Animal, Grupo BIOGEM, Sede Medellín, AA 1779, ColombiaUniversidad Nacional de Colombia, Facultad de Ciencias Agropecuarias, Departamento de Producción Animal, Grupo BIOGEM, Sede Medellín, AA 1779, ColombiaUniversidad Nacional de Colombia, Facultad de Ciencias Agropecuarias, Departamento de Producción Animal, Grupo BIOGEM, Sede Medellín, AA 1779, ColombiaABSTRACT Objective. To determine the association of intron 3 polymorphism of the bovine growth hormone (BGH) gene, with age at first service, first birth, first postpartum service and second birth in a population of Holstein cows in the state of Antioquia. Materials and methods. The study was conducted on 408 Holstein cows in 8 herds. Genotyping was performed using PCR-RFLP technique with DNA extracted from peripheral blood by the salting out technique. The Phenotypic information used was collected for 4 years, from a dairy production control program. To determine the association between characteristics and gene polymorphism, parametric statistical analyzes were performed as generalized linear models and linear regression analysis. Results. Allele frequency (positive) was 0.91 and was 0.09 for (negative) allele. Genotypic frequencies were 0.77, 0.2 and 0.03 for (positive/positive), (positive/negative) and (negative/negative) respectively. There were significant differences between the mean of age at first service, age at first birth, age at first postpartum service and age at second birth. For all of the (negative/negative) genotype characteristics there were greater ages for each event. Conclusions. These results suggest that intron-3 polymorphism of the BGH gene is associated with reproductive traits, facilitating the selection of individuals with favorable genotypes for use in breeding programs.http://revistas.unicordoba.edu.co/index.php/revistamvz/article/view/87Animal reproductionmolecular markersPCR-RFLP |
| spellingShingle | Juliana Arango G Julián Echeverri Z Albeiro López H Association of the bovine growth hormone gene with Holstein cattle reproductive parameters Revista MVZ Cordoba Animal reproduction molecular markers PCR-RFLP |
| title | Association of the bovine growth hormone gene with Holstein cattle reproductive parameters |
| title_full | Association of the bovine growth hormone gene with Holstein cattle reproductive parameters |
| title_fullStr | Association of the bovine growth hormone gene with Holstein cattle reproductive parameters |
| title_full_unstemmed | Association of the bovine growth hormone gene with Holstein cattle reproductive parameters |
| title_short | Association of the bovine growth hormone gene with Holstein cattle reproductive parameters |
| title_sort | association of the bovine growth hormone gene with holstein cattle reproductive parameters |
| topic | Animal reproduction molecular markers PCR-RFLP |
| url | http://revistas.unicordoba.edu.co/index.php/revistamvz/article/view/87 |
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