Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study

Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study

BackgroundAnthracyclines are associated with cardiotoxic effects. Cardiovascular biomarkers may reflect myocardial injury, dysfunction, inflammation, and fibrosis and may precede and predict the development of left ventricular impairment. The aim of this study was to assess: (1) longitudinal change...

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Bibliographic Details
Main Authors: Geeta Gulati, Siri L. Heck, Helge Røsjø, Anne H. Ree, Pavel Hoffmann, Tor‐Arne Hagve, Jon Norseth, Berit Gravdehaug, Kjetil Steine, Jürgen Geisler, Torbjørn Omland
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
beta‐blocker
brain natriuretic peptide
cardio‐oncology
C‐reactive protein
magnetic resonance imaging
troponin
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.006513

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