Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation
Granulomatosis with Polyangiitis (GPA) is a form of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We report a case of a 56-year-old man with GPA who first presented with acute urinary retention, and then developed pulmonarycavitating lesions and subarachnoid hemorrhage (SAH). Th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
World Scientific Publishing
2019-07-01
|
| Series: | Journal of Clinical Rheumatology and Immunology |
| Subjects: | |
| Online Access: | http://www.worldscientific.com/doi/epdf/10.1142/S2661341719720015 |
| _version_ | 1818360385846116352 |
|---|---|
| author | Raymond Bak Hei Chu Priscilla Ching Han Wong Joey Ka Ming Wai Florence Hiu Yi Yap |
| author_facet | Raymond Bak Hei Chu Priscilla Ching Han Wong Joey Ka Ming Wai Florence Hiu Yi Yap |
| author_sort | Raymond Bak Hei Chu |
| collection | DOAJ |
| description | Granulomatosis with Polyangiitis (GPA) is a form of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We report a case of a 56-year-old man with GPA who first presented with acute urinary retention, and then developed pulmonarycavitating lesions and subarachnoid hemorrhage (SAH). The SAH was due to a ruptured right vertebral artery aneurysm, whichwas subsequently embolized. The patient initially had a good response to immunosuppressive therapy but later succumbed due to fulminant sepsis. SAH is a rare complication of GPA and usually not associated with a detectable aneurysm. Our patient is thesecond case in the literature where an aneurysm had been detected on angiography and the first case where examination of the culprit aneurysm revealed features of vasculitis. |
| first_indexed | 2024-12-13T20:59:57Z |
| format | Article |
| id | doaj.art-fa4e858ec94d40968f854be0d91cb5d7 |
| institution | Directory Open Access Journal |
| issn | 2661-3417 2661-3425 |
| language | English |
| last_indexed | 2024-12-13T20:59:57Z |
| publishDate | 2019-07-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Clinical Rheumatology and Immunology |
| spelling | doaj.art-fa4e858ec94d40968f854be0d91cb5d72022-12-21T23:31:38ZengWorld Scientific PublishingJournal of Clinical Rheumatology and Immunology2661-34172661-34252019-07-01191343910.1142/S266134171972001510.1142/S2661341719720015Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical PresentationRaymond Bak Hei Chu0Priscilla Ching Han Wong1Joey Ka Ming Wai2Florence Hiu Yi Yap3Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Shatin, New Territories, Hong KongDivision of Rheumatology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, New Territories, Hong KongDepartment of Anaesthesia and Intensive Care, Prince of Wales Hospital, Shatin, New Territories, Hong KongDepartment of Anaesthesia and Intensive Care, Prince of Wales Hospital, Shatin, New Territories, Hong KongGranulomatosis with Polyangiitis (GPA) is a form of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We report a case of a 56-year-old man with GPA who first presented with acute urinary retention, and then developed pulmonarycavitating lesions and subarachnoid hemorrhage (SAH). The SAH was due to a ruptured right vertebral artery aneurysm, whichwas subsequently embolized. The patient initially had a good response to immunosuppressive therapy but later succumbed due to fulminant sepsis. SAH is a rare complication of GPA and usually not associated with a detectable aneurysm. Our patient is thesecond case in the literature where an aneurysm had been detected on angiography and the first case where examination of the culprit aneurysm revealed features of vasculitis.http://www.worldscientific.com/doi/epdf/10.1142/S2661341719720015wegener’s granulomatosis (wg)granulomatosis with polyangiitis (gpa)anti-neutrophil cytoplasmic autoantibody (anca)subarachnoid hemorrhage (sah)intracranial hemorrhage (ich)neurologicalurologicalprostateretention of urinepulmonarycavitation |
| spellingShingle | Raymond Bak Hei Chu Priscilla Ching Han Wong Joey Ka Ming Wai Florence Hiu Yi Yap Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation Journal of Clinical Rheumatology and Immunology wegener’s granulomatosis (wg) granulomatosis with polyangiitis (gpa) anti-neutrophil cytoplasmic autoantibody (anca) subarachnoid hemorrhage (sah) intracranial hemorrhage (ich) neurological urological prostate retention of urine pulmonary cavitation |
| title | Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation |
| title_full | Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation |
| title_fullStr | Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation |
| title_full_unstemmed | Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation |
| title_short | Subarachnoid Hemorrhage and Prostatic Involvement in Granulomatosis with Polyangiitis – An Atypical Presentation |
| title_sort | subarachnoid hemorrhage and prostatic involvement in granulomatosis with polyangiitis an atypical presentation |
| topic | wegener’s granulomatosis (wg) granulomatosis with polyangiitis (gpa) anti-neutrophil cytoplasmic autoantibody (anca) subarachnoid hemorrhage (sah) intracranial hemorrhage (ich) neurological urological prostate retention of urine pulmonary cavitation |
| url | http://www.worldscientific.com/doi/epdf/10.1142/S2661341719720015 |
| work_keys_str_mv | AT raymondbakheichu subarachnoidhemorrhageandprostaticinvolvementingranulomatosiswithpolyangiitisanatypicalpresentation AT priscillachinghanwong subarachnoidhemorrhageandprostaticinvolvementingranulomatosiswithpolyangiitisanatypicalpresentation AT joeykamingwai subarachnoidhemorrhageandprostaticinvolvementingranulomatosiswithpolyangiitisanatypicalpresentation AT florencehiuyiyap subarachnoidhemorrhageandprostaticinvolvementingranulomatosiswithpolyangiitisanatypicalpresentation |