High-order functional redundancy in ageing explained via alterations in the connectome in a whole-brain model.

The human brain generates a rich repertoire of spatio-temporal activity patterns, which support a wide variety of motor and cognitive functions. These patterns of activity change with age in a multi-factorial manner. One of these factors is the variations in the brain's connectomics that occurs...

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Bibliographic Details
Main Authors: Marilyn Gatica, Fernando E Rosas, Pedro A M Mediano, Ibai Diez, Stephan P Swinnen, Patricio Orio, Rodrigo Cofré, Jesus M Cortes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010431