Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study
Objective: To investigate the spatial heterogeneity of nontuberculous mycobacterial pulmonary disease (NTM-PD) in Shanghai. Methods: A population-based retrospective study was conducted using presumptive pulmonary tuberculosis surveillance data of Shanghai between 2010 and 2019. The study described...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971224000729 |
| _version_ | 1797220640893173760 |
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| author | Yangyi Zhang Ruoyao Sun Chenlei Yu Jing Li Honghua Lin Jinrong Huang Ying Wang Xin Shen Yuan Jiang Chongguang Yang Biao Xu |
| author_facet | Yangyi Zhang Ruoyao Sun Chenlei Yu Jing Li Honghua Lin Jinrong Huang Ying Wang Xin Shen Yuan Jiang Chongguang Yang Biao Xu |
| author_sort | Yangyi Zhang |
| collection | DOAJ |
| description | Objective: To investigate the spatial heterogeneity of nontuberculous mycobacterial pulmonary disease (NTM-PD) in Shanghai. Methods: A population-based retrospective study was conducted using presumptive pulmonary tuberculosis surveillance data of Shanghai between 2010 and 2019. The study described the spatial distribution of NTM-PD notification rates, employing hierarchical Bayesian mapping for high-risk areas and the Getis-Ord Gi* statistic to identify hot spots and explore associated factors. Results: Of 1652 NTM-PD cases, the most common species was Mycobacterium kansasii complex (MKC) (41.9%), followed by Mycobacterium avium complex (MAC) (27.1%) and Mycobacterium abscessus complex (MABC) (16.2%). MKC-PD patients were generally younger males with a higher incidence of pulmonary cavities, while MAC-PD patients were more often farmers or had a history of tuberculosis treatment. MKC-PD hot spots were primarily located in the areas alongside the Huangpu River, while MAC-PD hot spots were mainly in the western agricultural areas. Patients with MKC-PD and MAC-PD exhibited a higher risk of spatial clustering compared to those with MABC-PD. Conclusions: Different types of NTM-PD exhibit distinct patterns of spatial clustering and are associated with various factors. These findings underscore the importance of environmental and host factors in the epidemic of NTM-PD. |
| first_indexed | 2024-04-24T12:52:46Z |
| format | Article |
| id | doaj.art-fa53f4bf29ac4eef8c189b17652a1ec2 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-04-24T12:52:46Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-fa53f4bf29ac4eef8c189b17652a1ec22024-04-06T04:39:34ZengElsevierInternational Journal of Infectious Diseases1201-97122024-06-01143107001Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based StudyYangyi Zhang0Ruoyao Sun1Chenlei Yu2Jing Li3Honghua Lin4Jinrong Huang5Ying Wang6Xin Shen7Yuan Jiang8Chongguang Yang9Biao Xu10Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety (Ministry of Education), Fudan University, Shanghai, P. R. China; Division of TB and HIV/AIDS Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, P. R. China; Shanghai Institutes of Preventive Medicine, Shanghai, P. R. ChinaSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, P. R. ChinaDivision of TB and HIV/AIDS Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, P. R. China; Shanghai Institutes of Preventive Medicine, Shanghai, P. R. ChinaDivision of TB and HIV/AIDS Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, P. R. China; Shanghai Institutes of Preventive Medicine, Shanghai, P. R. ChinaSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, P. R. ChinaSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, P. R. China; Nanshan District Center for Disease Control and Prevention, Shenzhen, P. R. ChinaNanshan District Center for Disease Control and Prevention, Shenzhen, P. R. ChinaDivision of TB and HIV/AIDS Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, P. R. China; Shanghai Institutes of Preventive Medicine, Shanghai, P. R. ChinaDivision of TB and HIV/AIDS Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, P. R. China; Shanghai Institutes of Preventive Medicine, Shanghai, P. R. ChinaSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, P. R. China; Nanshan District Center for Disease Control and Prevention, Shenzhen, P. R. ChinaDepartment of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety (Ministry of Education), Fudan University, Shanghai, P. R. China; Corresponding author: Biao Xu, Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety (Ministry of Education), Fudan University, 130 Dong An Road, Shanghai 200032, P. R. China.Objective: To investigate the spatial heterogeneity of nontuberculous mycobacterial pulmonary disease (NTM-PD) in Shanghai. Methods: A population-based retrospective study was conducted using presumptive pulmonary tuberculosis surveillance data of Shanghai between 2010 and 2019. The study described the spatial distribution of NTM-PD notification rates, employing hierarchical Bayesian mapping for high-risk areas and the Getis-Ord Gi* statistic to identify hot spots and explore associated factors. Results: Of 1652 NTM-PD cases, the most common species was Mycobacterium kansasii complex (MKC) (41.9%), followed by Mycobacterium avium complex (MAC) (27.1%) and Mycobacterium abscessus complex (MABC) (16.2%). MKC-PD patients were generally younger males with a higher incidence of pulmonary cavities, while MAC-PD patients were more often farmers or had a history of tuberculosis treatment. MKC-PD hot spots were primarily located in the areas alongside the Huangpu River, while MAC-PD hot spots were mainly in the western agricultural areas. Patients with MKC-PD and MAC-PD exhibited a higher risk of spatial clustering compared to those with MABC-PD. Conclusions: Different types of NTM-PD exhibit distinct patterns of spatial clustering and are associated with various factors. These findings underscore the importance of environmental and host factors in the epidemic of NTM-PD.http://www.sciencedirect.com/science/article/pii/S1201971224000729Nontuberculous mycobacterial pulmonary diseaseSpatial heterogeneityRisk factorsSpatial distributionBayesian disease mapping |
| spellingShingle | Yangyi Zhang Ruoyao Sun Chenlei Yu Jing Li Honghua Lin Jinrong Huang Ying Wang Xin Shen Yuan Jiang Chongguang Yang Biao Xu Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study International Journal of Infectious Diseases Nontuberculous mycobacterial pulmonary disease Spatial heterogeneity Risk factors Spatial distribution Bayesian disease mapping |
| title | Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study |
| title_full | Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study |
| title_fullStr | Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study |
| title_full_unstemmed | Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study |
| title_short | Spatial Heterogeneity of Nontuberculous Mycobacterial Pulmonary Disease in Shanghai: Insights from a Ten-Year Population-Based Study |
| title_sort | spatial heterogeneity of nontuberculous mycobacterial pulmonary disease in shanghai insights from a ten year population based study |
| topic | Nontuberculous mycobacterial pulmonary disease Spatial heterogeneity Risk factors Spatial distribution Bayesian disease mapping |
| url | http://www.sciencedirect.com/science/article/pii/S1201971224000729 |
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