In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system
Although an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic mel...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Medical Ultrasound |
| Subjects: | |
| Online Access: | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=1;spage=50;epage=52;aulast= |
| _version_ | 1818928417758773248 |
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| author | Tomoyuki Ohta Takako Shirakawa Shinya Okada Naohiro Ishii Shigeru Kiryu |
| author_facet | Tomoyuki Ohta Takako Shirakawa Shinya Okada Naohiro Ishii Shigeru Kiryu |
| author_sort | Tomoyuki Ohta |
| collection | DOAJ |
| description | Although an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic melanoma in the lymph nodes of specimens prepared for microscopic examination. The PA effect was not obvious in amelanotic melanoma, but was seen in melanotic melanoma by PA imaging (PAI) and histopathological correlation in cases of primary melanotic melanoma accompanied by metastatic lymph nodes, including the coexistence of amelanotic melanoma and melanotic melanoma. Clinical workup should be performed with not only PAI but also conventional ultrasonography in cases with metastasis related to amelanotic transformation, which would likely be missed by PAI alone. |
| first_indexed | 2024-12-20T03:28:35Z |
| format | Article |
| id | doaj.art-fa5401283c764cd389548e0d20b2dcf0 |
| institution | Directory Open Access Journal |
| issn | 0929-6441 2212-1552 |
| language | English |
| last_indexed | 2024-12-20T03:28:35Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Ultrasound |
| spelling | doaj.art-fa5401283c764cd389548e0d20b2dcf02022-12-21T19:55:02ZengWolters Kluwer Medknow PublicationsJournal of Medical Ultrasound0929-64412212-15522021-01-01291505210.4103/JMU.JMU_121_19In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging systemTomoyuki OhtaTakako ShirakawaShinya OkadaNaohiro IshiiShigeru KiryuAlthough an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic melanoma in the lymph nodes of specimens prepared for microscopic examination. The PA effect was not obvious in amelanotic melanoma, but was seen in melanotic melanoma by PA imaging (PAI) and histopathological correlation in cases of primary melanotic melanoma accompanied by metastatic lymph nodes, including the coexistence of amelanotic melanoma and melanotic melanoma. Clinical workup should be performed with not only PAI but also conventional ultrasonography in cases with metastasis related to amelanotic transformation, which would likely be missed by PAI alone.http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=1;spage=50;epage=52;aulast=amelanotic melanomamelanomaphotoacoustic ultrasound imaging |
| spellingShingle | Tomoyuki Ohta Takako Shirakawa Shinya Okada Naohiro Ishii Shigeru Kiryu In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system Journal of Medical Ultrasound amelanotic melanoma melanoma photoacoustic ultrasound imaging |
| title | In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system |
| title_full | In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system |
| title_fullStr | In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system |
| title_full_unstemmed | In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system |
| title_short | In vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system |
| title_sort | in vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light emitting diode based multispectral photoacoustic ultrasound imaging system |
| topic | amelanotic melanoma melanoma photoacoustic ultrasound imaging |
| url | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=1;spage=50;epage=52;aulast= |
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