The role of microglia in adult hippocampus neurogenesis
Our view of microglia has dramatically changed in the last decade. From cells being silent in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions, including adult hippocampal neurogenesis, cognitive and behavioral function. In light of recent...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-11-01
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| Series: | Frontiers in Cellular Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00229/full |
| _version_ | 1818293279651790848 |
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| author | Carmelina eGemma Adam D Bachstetter |
| author_facet | Carmelina eGemma Adam D Bachstetter |
| author_sort | Carmelina eGemma |
| collection | DOAJ |
| description | Our view of microglia has dramatically changed in the last decade. From cells being silent in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions, including adult hippocampal neurogenesis, cognitive and behavioral function. In light of recent discoveries revealing a role of microglia as important effectors of neuronal circuit reorganization, considerable attention has been focused on how microglia and hippocampal neurogenesis could be an interdependent phenomenon. In this review the role of microglia in the adult hippocampal neurogenesis under physiological condition will be discussed. |
| first_indexed | 2024-12-13T03:13:20Z |
| format | Article |
| id | doaj.art-fa58a1cd9441435987c0da0d4594cae3 |
| institution | Directory Open Access Journal |
| issn | 1662-5102 |
| language | English |
| last_indexed | 2024-12-13T03:13:20Z |
| publishDate | 2013-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular Neuroscience |
| spelling | doaj.art-fa58a1cd9441435987c0da0d4594cae32022-12-22T00:01:32ZengFrontiers Media S.A.Frontiers in Cellular Neuroscience1662-51022013-11-01710.3389/fncel.2013.0022946146The role of microglia in adult hippocampus neurogenesisCarmelina eGemma0Adam D Bachstetter1University of WashingtonUniversity of KentuckyOur view of microglia has dramatically changed in the last decade. From cells being silent in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions, including adult hippocampal neurogenesis, cognitive and behavioral function. In light of recent discoveries revealing a role of microglia as important effectors of neuronal circuit reorganization, considerable attention has been focused on how microglia and hippocampal neurogenesis could be an interdependent phenomenon. In this review the role of microglia in the adult hippocampal neurogenesis under physiological condition will be discussed.http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00229/fullChemokinesMicrogliaNeurogenesisCognitive FunctionFractalkineCX3CR1 |
| spellingShingle | Carmelina eGemma Adam D Bachstetter The role of microglia in adult hippocampus neurogenesis Frontiers in Cellular Neuroscience Chemokines Microglia Neurogenesis Cognitive Function Fractalkine CX3CR1 |
| title | The role of microglia in adult hippocampus neurogenesis |
| title_full | The role of microglia in adult hippocampus neurogenesis |
| title_fullStr | The role of microglia in adult hippocampus neurogenesis |
| title_full_unstemmed | The role of microglia in adult hippocampus neurogenesis |
| title_short | The role of microglia in adult hippocampus neurogenesis |
| title_sort | role of microglia in adult hippocampus neurogenesis |
| topic | Chemokines Microglia Neurogenesis Cognitive Function Fractalkine CX3CR1 |
| url | http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00229/full |
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