(Thyroid) Hormonal regulation of breast cancer cells

(Thyroid) Hormonal regulation of breast cancer cells

Thyroid hormone as L-thyroxine (T4) acts nongenomically at physiological concentrations at its cancer cell surface receptor on integrin αvβ3 (‘thyrointegrin’) to cause cancer cell proliferation. In the case of estrogen receptor (ERα)-positive breast cancer cells, T4 via the integrin promotes ERα-dep...

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Bibliographic Details
Main Authors: Aleck Hercbergs, Hung-Yun Lin, Shaker A. Mousa, Paul J. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
L-thyroxine (T4)
3
5
3’-triiodo-L-thyronine(T3)
integrin αvβ3
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1109555/full

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