Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide

Background. Herbal medication for hypertension is common in population. This study aims to seek the role of nitric oxide (NO) in the mechanism of blood pressure reduction after  administration of rosella tea (hisbiscus sabdariffa). Methods. A pre-post study was conducted in elderly hypertensive wom...

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Main Authors: I Yusni, M Syahrul
Format: Article
Language:English
Published: Indonesian Heart Association 2013-06-01
Series:Majalah Kardiologi Indonesia
Subjects:
Online Access:http://ijconline.id/index.php/ijc/article/view/38
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author I Yusni
M Syahrul
author_facet I Yusni
M Syahrul
author_sort I Yusni
collection DOAJ
description Background. Herbal medication for hypertension is common in population. This study aims to seek the role of nitric oxide (NO) in the mechanism of blood pressure reduction after  administration of rosella tea (hisbiscus sabdariffa). Methods. A pre-post study was conducted in elderly hypertensive women at UPTD Rumoh Sejahtera Banda Aceh. Subjects were given 2 grams rosella tea after meal twice a day for 3 weeks.  Sistolic and diastolic blood pressure, and NO concentration were compare pre and post rosella administration between control and experiment groups. Results. Rosela group has lower systolic and diastolic pressure as compare to control group (140,00 ± 10,00 vs 142,85 ± 4.87 mmHg; 84,28 ± 5,34 vs 89,28 ± 4,87mmHg, p < 0.05  respectively). Systolic pressure reduction by rosella was 14,77% with average pressure reduction of 24,28 mmHg. Diastolic pressure reduction was 9,22% with averagepressure reduction of 8,57 mmHg. No significant difference of nitric oxide concentration between groups (4,85 ± 2,16 vs 4,55 ± 3,11 µM, p>0.05). Conclusion. Rosella reduce systolic and diastolic blood pressure of elderly hypertensive women with mechanism out of nitric oxide level.
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spelling doaj.art-fa61f30906434555a0757a28905685eb2022-12-21T23:00:20ZengIndonesian Heart AssociationMajalah Kardiologi Indonesia0126-37732620-47622013-06-0133310.30701/ijc.v33i3.38Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric OxideI Yusni0M Syahrul1Bagian Fisiologi Fakultas Ke-dokteran Universitas Syiah Kuala, Banda AcehBagian Neurologi Fakultas Ke-dokteran Universitas Syiah Kuala, Banda AcehBackground. Herbal medication for hypertension is common in population. This study aims to seek the role of nitric oxide (NO) in the mechanism of blood pressure reduction after  administration of rosella tea (hisbiscus sabdariffa). Methods. A pre-post study was conducted in elderly hypertensive women at UPTD Rumoh Sejahtera Banda Aceh. Subjects were given 2 grams rosella tea after meal twice a day for 3 weeks.  Sistolic and diastolic blood pressure, and NO concentration were compare pre and post rosella administration between control and experiment groups. Results. Rosela group has lower systolic and diastolic pressure as compare to control group (140,00 ± 10,00 vs 142,85 ± 4.87 mmHg; 84,28 ± 5,34 vs 89,28 ± 4,87mmHg, p < 0.05  respectively). Systolic pressure reduction by rosella was 14,77% with average pressure reduction of 24,28 mmHg. Diastolic pressure reduction was 9,22% with averagepressure reduction of 8,57 mmHg. No significant difference of nitric oxide concentration between groups (4,85 ± 2,16 vs 4,55 ± 3,11 µM, p>0.05). Conclusion. Rosella reduce systolic and diastolic blood pressure of elderly hypertensive women with mechanism out of nitric oxide level.http://ijconline.id/index.php/ijc/article/view/38nitric oxiderosellaelderlyhypertension
spellingShingle I Yusni
M Syahrul
Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide
Majalah Kardiologi Indonesia
nitric oxide
rosella
elderly
hypertension
title Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide
title_full Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide
title_fullStr Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide
title_full_unstemmed Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide
title_short Blood Pressure Reduction By Rosela ( Hisbiscus Sabdariffa) in Elderly Women: Role of Vasodilation Response of Nitric Oxide
title_sort blood pressure reduction by rosela hisbiscus sabdariffa in elderly women role of vasodilation response of nitric oxide
topic nitric oxide
rosella
elderly
hypertension
url http://ijconline.id/index.php/ijc/article/view/38
work_keys_str_mv AT iyusni bloodpressurereductionbyroselahisbiscussabdariffainelderlywomenroleofvasodilationresponseofnitricoxide
AT msyahrul bloodpressurereductionbyroselahisbiscussabdariffainelderlywomenroleofvasodilationresponseofnitricoxide