A Bayesian framework to integrate multi-level genome-scale data for Autism risk gene prioritization

A Bayesian framework to integrate multi-level genome-scale data for Autism risk gene prioritization

Abstract Background Autism spectrum disorder (ASD) is a group of complex neurodevelopment disorders with a strong genetic basis. Large scale sequencing studies have identified over one hundred ASD risk genes. Nevertheless, the vast majority of ASD risk genes remain to be discovered, as it is estimat...

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Bibliographic Details
Main Authors: Ying Ji, Rui Chen, Quan Wang, Qiang Wei, Ran Tao, Bingshan Li
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Bioinformatics
Subjects:
Gene prioritization
Bayesian model selection
ASD risk genes
Online Access:https://doi.org/10.1186/s12859-022-04616-y

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