Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study
Background: The Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the presen...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/14/2/199 |
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| author | Antonios Dakanalis Christina Tryfonos Eleni Pavlidou Konstantinos Vadikolias Sousana K. Papadopoulou Olga Alexatou Theofanis Vorvolakos Maria Chrysafi Dimitrios Fotiou Maria Mentzelou Aspasia Serdari Maria Chatzidimitriou Sophia Dimoliani Gerasimos Tsourouflis Constantinos Giaginis |
| author_facet | Antonios Dakanalis Christina Tryfonos Eleni Pavlidou Konstantinos Vadikolias Sousana K. Papadopoulou Olga Alexatou Theofanis Vorvolakos Maria Chrysafi Dimitrios Fotiou Maria Mentzelou Aspasia Serdari Maria Chatzidimitriou Sophia Dimoliani Gerasimos Tsourouflis Constantinos Giaginis |
| author_sort | Antonios Dakanalis |
| collection | DOAJ |
| description | Background: The Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is to evaluate the potential effects of MD compliance on disease disability, quality of life, physical activity, depressive symptomatology, and blood biochemical parameters related to nutritional status in MS patients, considering several socio-demographic, anthropometric, and lifestyle characteristics. Methods: This is a cross-sectional study conducted on 558 adults with MS aged 18–64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients’ medical records. Results: Enhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition. Conclusions: The present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results. |
| first_indexed | 2024-03-07T22:25:17Z |
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| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-07T22:25:17Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
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| series | Journal of Personalized Medicine |
| spelling | doaj.art-fa68a28b44444054a22636454c157b782024-02-23T15:23:50ZengMDPI AGJournal of Personalized Medicine2075-44262024-02-0114219910.3390/jpm14020199Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional StudyAntonios Dakanalis0Christina Tryfonos1Eleni Pavlidou2Konstantinos Vadikolias3Sousana K. Papadopoulou4Olga Alexatou5Theofanis Vorvolakos6Maria Chrysafi7Dimitrios Fotiou8Maria Mentzelou9Aspasia Serdari10Maria Chatzidimitriou11Sophia Dimoliani12Gerasimos Tsourouflis13Constantinos Giaginis14Department of Mental Health, Fondazione IRCCS San Gerardo dei Tintori, Via G.B. Pergolesi 33, 20900 Monza, ItalyDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceDepartment of Neurology, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, GreeceDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceDepartment of Psychiatry, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceDepartment of Neurology, School of Medicine, Aristoteleio University of Thessaloniki, 54124 Thessaloniki, GreeceDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceDepartment of Psychiatry, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Biomedical Sciences, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, GreeceDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceSecond Department of Surgery, Propedeutic, National and Kapodistrian University of Athens, Laikon General Hospital, 11527 Athens, GreeceDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400 Lemnos, GreeceBackground: The Mediterranean diet (MD) is well-known as a diet which may exert a protective effect against neurodegenerative diseases, including multiple sclerosis (MS). To date, only a few clinical surveys have assessed the potential effects of the MD in patients with MS. The purpose of the present study is to evaluate the potential effects of MD compliance on disease disability, quality of life, physical activity, depressive symptomatology, and blood biochemical parameters related to nutritional status in MS patients, considering several socio-demographic, anthropometric, and lifestyle characteristics. Methods: This is a cross-sectional study conducted on 558 adults with MS aged 18–64 years. Relevant questionnaires were utilized to evaluate socio-demographic and anthropometric parameters, disease disability (Expanded Disability Status Scale, EDSS), multidimensional health-related quality (MS Quality of Life-54, MSQOL-54), physical activity levels (International Physical Activity Questionnaire, IPAQ), depression (Beck Depression Inventory II, BDI-II), and MD adherence (MedDietScore), while several blood biochemical parameters were retrieved from the patients’ medical records. Results: Enhanced MD compliance was independently associated with a decreased frequency of overweight/obesity, as well as abdominal obesity, in patients suffering from MS. Elevated MD compliance was also independently associated with a decreased incidence of advanced disease disability, a higher prevalence of elevated physical activity, an improved quality of life, and lower depressive symptoms, as well as higher levels of certain blood biochemical parameters, which are effective indicators of iron deficiency and malnutrition. Conclusions: The present study found that higher MD adherence may slow down disease disability, promoting a better quality of life and mental health in adults with MS. Future prospective surveys are required to obtain conclusive results.https://www.mdpi.com/2075-4426/14/2/199multiple sclerosisdisease disabilityquality of lifephysical activityserum biomarkersMediterranean diet |
| spellingShingle | Antonios Dakanalis Christina Tryfonos Eleni Pavlidou Konstantinos Vadikolias Sousana K. Papadopoulou Olga Alexatou Theofanis Vorvolakos Maria Chrysafi Dimitrios Fotiou Maria Mentzelou Aspasia Serdari Maria Chatzidimitriou Sophia Dimoliani Gerasimos Tsourouflis Constantinos Giaginis Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study Journal of Personalized Medicine multiple sclerosis disease disability quality of life physical activity serum biomarkers Mediterranean diet |
| title | Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study |
| title_full | Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study |
| title_fullStr | Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study |
| title_full_unstemmed | Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study |
| title_short | Associations between Mediterranean Diet Adherence, Quality of Life, and Mental Health in Patients with Multiple Sclerosis: A Cross-Sectional Study |
| title_sort | associations between mediterranean diet adherence quality of life and mental health in patients with multiple sclerosis a cross sectional study |
| topic | multiple sclerosis disease disability quality of life physical activity serum biomarkers Mediterranean diet |
| url | https://www.mdpi.com/2075-4426/14/2/199 |
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