Reverse cardio-oncology: A budding concept

Having established the significance of cardiovascular side-effects of anti-neoplastic drugs, present day cardio-oncology has forayed into newer territories buoyed by research into the multiple connections that exist between cardiovascular disease and cancer. An emerging concept of reverse cardio-onc...

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Bibliografski detalji
Glavni autori: Chhabi Satpathy, Trinath Kumar Mishra, Subhasish Singh, Anshu Kumar Jha
Format: Članak
Jezik:English
Izdano: Elsevier 2023-11-01
Serija:Indian Heart Journal
Teme:
Online pristup:http://www.sciencedirect.com/science/article/pii/S0019483223001633
Opis
Sažetak:Having established the significance of cardiovascular side-effects of anti-neoplastic drugs, present day cardio-oncology has forayed into newer territories buoyed by research into the multiple connections that exist between cardiovascular disease and cancer. An emerging concept of reverse cardio-oncology focuses on the heightened risk of cancer in patients with cardiovascular disease. Common mechanistics of cancer and heart failure (HF) like chronic inflammation and clonal haematopoesis as well as common predisposing factors like obesity and diabetes underline the relation between both cardiovascular disease and various cancers.This review discusses the potential magnitude of the problem, the underlying pathophysiological mechanisms and classification of this novel subject.
ISSN:0019-4832