NGS Panel Testing of Triple-Negative Breast Cancer Patients in Cyprus: A Study of <i>BRCA</i>-Negative Cases

NGS Panel Testing of Triple-Negative Breast Cancer Patients in Cyprus: A Study of <i>BRCA</i>-Negative Cases

In Cyprus, approximately 9% of triple-negative (estrogen receptor-negative, progesterone receptor-negative, and human epidermal growth factor receptor 2-negative) breast cancer (TNBC) patients are positive for germline pathogenic variants (PVs) in <i>BRCA1/2</i>. However, the contributio...

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Bibliographic Details
Main Authors: Maria Zanti, Maria A. Loizidou, Kyriaki Michailidou, Panagiota Pirpa, Christina Machattou, Yiola Marcou, Flora Kyriakou, Eleni Kakouri, George A. Tanteles, Elena Spanou, George M. Spyrou, Kyriacos Kyriacou, Andreas Hadjisavvas
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
triple-negative breast cancer
germline genetic testing
NGS of gene panels
genetic predisposition to breast cancer
Online Access:https://www.mdpi.com/2072-6694/12/11/3140

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