Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral

Two new briarane diterpenoids, briarenolides, F (<strong>1</strong>) and G (<strong>2</strong>), were isolated from an octocoral identified as <em>Briareum</em> sp. The structures of briaranes <strong>1...

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Main Authors: Jyh-Horng Sheu, Nai-Cheng Lin, Yueh-Hsiung Kuo, Zhi-Hong Wen, Ching-Feng Weng, Chia-Hung Lee, Yung-Husan Chen, Tsong-Long Hwang, Pei-Han Hong, Yin-Di Su, Ping-Jyun Sung, Jui-Hsin Su
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/10/5/1156
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author Jyh-Horng Sheu
Nai-Cheng Lin
Yueh-Hsiung Kuo
Zhi-Hong Wen
Ching-Feng Weng
Chia-Hung Lee
Yung-Husan Chen
Tsong-Long Hwang
Pei-Han Hong
Yin-Di Su
Ping-Jyun Sung
Jui-Hsin Su
author_facet Jyh-Horng Sheu
Nai-Cheng Lin
Yueh-Hsiung Kuo
Zhi-Hong Wen
Ching-Feng Weng
Chia-Hung Lee
Yung-Husan Chen
Tsong-Long Hwang
Pei-Han Hong
Yin-Di Su
Ping-Jyun Sung
Jui-Hsin Su
author_sort Jyh-Horng Sheu
collection DOAJ
description Two new briarane diterpenoids, briarenolides, F (<strong>1</strong>) and G (<strong>2</strong>), were isolated from an octocoral identified as <em>Briareum</em> sp. The structures of briaranes <strong>1</strong> and <strong>2</strong> were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F was proven to be the first 6-hydroperoxybriarane derivative and this compound displayed a significant inhibitory effect on the generation of superoxide anion by human neutrophils.
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spelling doaj.art-fa716c64d40547c2967aa255f4979cab2022-12-22T02:17:57ZengMDPI AGMarine Drugs1660-33972012-05-011051156116810.3390/md10051156Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. OctocoralJyh-Horng SheuNai-Cheng LinYueh-Hsiung KuoZhi-Hong WenChing-Feng WengChia-Hung LeeYung-Husan ChenTsong-Long HwangPei-Han HongYin-Di SuPing-Jyun SungJui-Hsin SuTwo new briarane diterpenoids, briarenolides, F (<strong>1</strong>) and G (<strong>2</strong>), were isolated from an octocoral identified as <em>Briareum</em> sp. The structures of briaranes <strong>1</strong> and <strong>2</strong> were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F was proven to be the first 6-hydroperoxybriarane derivative and this compound displayed a significant inhibitory effect on the generation of superoxide anion by human neutrophils.http://www.mdpi.com/1660-3397/10/5/1156briarenolidebriarane<em>Briareum</em>superoxide anion
spellingShingle Jyh-Horng Sheu
Nai-Cheng Lin
Yueh-Hsiung Kuo
Zhi-Hong Wen
Ching-Feng Weng
Chia-Hung Lee
Yung-Husan Chen
Tsong-Long Hwang
Pei-Han Hong
Yin-Di Su
Ping-Jyun Sung
Jui-Hsin Su
Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral
Marine Drugs
briarenolide
briarane
<em>Briareum</em>
superoxide anion
title Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral
title_full Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral
title_fullStr Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral
title_full_unstemmed Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral
title_short Briarenolides F and G, New Briarane Diterpenoids from a <em>Briareum</em> sp. Octocoral
title_sort briarenolides f and g new briarane diterpenoids from a lt em gt briareum lt em gt sp octocoral
topic briarenolide
briarane
<em>Briareum</em>
superoxide anion
url http://www.mdpi.com/1660-3397/10/5/1156
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