Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents

AIM: To observe the effect of combining partial reduction orthokeratology(Ortho-K)and spectacles on slowing myopic progressionin high myopic adolescent.<p>METHODS: Sixty-nine eyes of 36 high myopic adolescent(aged 9~15 years)with spherical equivalent refraction ≥-6.00 diopters(D)(spherical com...

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Main Authors: Ming Luo, Sheng-Sheng Ma, Hong-Yang Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-01-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2015/1/201501037.pdf
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author Ming Luo
Sheng-Sheng Ma
Hong-Yang Li
author_facet Ming Luo
Sheng-Sheng Ma
Hong-Yang Li
author_sort Ming Luo
collection DOAJ
description AIM: To observe the effect of combining partial reduction orthokeratology(Ortho-K)and spectacles on slowing myopic progressionin high myopic adolescent.<p>METHODS: Sixty-nine eyes of 36 high myopic adolescent(aged 9~15 years)with spherical equivalent refraction ≥-6.00 diopters(D)(spherical component ≥-5.50D)were fitted with custom-made four-zone/five-curve Ortho-K lenses. The target of reduction was to achieve -5.00D for both eyes. The residual refractive errors after at least one month of Ortho-K wear were corrected with single-vision spectacles for clear vision in the daytime. The unaided visual acuity(UVA), refractive error(RE), axial length(AL), and ocular health were assessed before the Ortho-K lens wear, and followed up for 2a after Ortho-K.<p>RESULTS:(1)Changes in UVA: The mean UVA was 0.09±0.05 at baseline before Ortho-K; the mean UVA was 0.27±0.14, 0.54±0.18, 0.78±0.24, and 0.81±0.19, respectively after Ortho-K wear for l night, 1wk, 1, and 3mo. The differences of UVA were significant with baseline(<i>P</i><0.05), and became stable 1mo after the treatment.(2)Changes in RE: The mean RE was -6.82±0.71D at baseline before Ortho-K and -6.86±0.77D after Ortho-K wear for 1a(<i>P</i>>0.05 compared to baseline). The mean RE was -7.11±0.81D after Ortho-K wear for 2a, and the amount of myopia increased -0.29±0.37D compared to baseline(<i>P</i><0.05).(3)Changes in AL: The mean AL was 26.18±0.57mm at baseline before Ortho-K, and it was not significantly different(<i>P</i>>0.05)from the AL after Ortho-K wear for 6mo(26.19±0.54mm)and for 1a(26.21±0.47mm). The AL was 26.37±0.59mm after Ortho-K wear for 2a, and the mean increase was 0.19±0.28mm compared to baseline(<i>P</i><0.05).(4)Grade 1 corneal staining was observed in some subjects at each visit. However, the staining was improved after lens cleaning, discontinuing lens wear, or applying artificial tears. No other adverse events were reported in all subjects during the 2a study. <p>CONCLUSION:Combining partial reduction Ortho-K and spectacles completely slowed myopic progression in high myopic adolescent after receiving the treatment for 1a, and partially reduced myopia progression after 2a of treatment. No severe ocular complications were found throughout the treatment. The combination treatment appeared to be effective and safe, but its long-term effect needs to be further assessed.
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spelling doaj.art-fa7180313d8643a3a20b3c5663d6cbbb2022-12-22T02:32:04ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-01-0115112813010.3980/j.issn.1672-5123.2015.1.37Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescentsMing Luo0Sheng-Sheng Ma1Hong-Yang Li2Department of Ophthalmology, School of Medical, the Fourth Affiliated Hospital of Jinan University, Guangzhou Red Cross Hospital, Guangzhou 510220, Guangdong Province, ChinaDepartment of Ophthalmology, School of Medical, the Fourth Affiliated Hospital of Jinan University, Guangzhou Red Cross Hospital, Guangzhou 510220, Guangdong Province, ChinaDepartment of Ophthalmology, School of Medical, the Fourth Affiliated Hospital of Jinan University, Guangzhou Red Cross Hospital, Guangzhou 510220, Guangdong Province, ChinaAIM: To observe the effect of combining partial reduction orthokeratology(Ortho-K)and spectacles on slowing myopic progressionin high myopic adolescent.<p>METHODS: Sixty-nine eyes of 36 high myopic adolescent(aged 9~15 years)with spherical equivalent refraction ≥-6.00 diopters(D)(spherical component ≥-5.50D)were fitted with custom-made four-zone/five-curve Ortho-K lenses. The target of reduction was to achieve -5.00D for both eyes. The residual refractive errors after at least one month of Ortho-K wear were corrected with single-vision spectacles for clear vision in the daytime. The unaided visual acuity(UVA), refractive error(RE), axial length(AL), and ocular health were assessed before the Ortho-K lens wear, and followed up for 2a after Ortho-K.<p>RESULTS:(1)Changes in UVA: The mean UVA was 0.09±0.05 at baseline before Ortho-K; the mean UVA was 0.27±0.14, 0.54±0.18, 0.78±0.24, and 0.81±0.19, respectively after Ortho-K wear for l night, 1wk, 1, and 3mo. The differences of UVA were significant with baseline(<i>P</i><0.05), and became stable 1mo after the treatment.(2)Changes in RE: The mean RE was -6.82±0.71D at baseline before Ortho-K and -6.86±0.77D after Ortho-K wear for 1a(<i>P</i>>0.05 compared to baseline). The mean RE was -7.11±0.81D after Ortho-K wear for 2a, and the amount of myopia increased -0.29±0.37D compared to baseline(<i>P</i><0.05).(3)Changes in AL: The mean AL was 26.18±0.57mm at baseline before Ortho-K, and it was not significantly different(<i>P</i>>0.05)from the AL after Ortho-K wear for 6mo(26.19±0.54mm)and for 1a(26.21±0.47mm). The AL was 26.37±0.59mm after Ortho-K wear for 2a, and the mean increase was 0.19±0.28mm compared to baseline(<i>P</i><0.05).(4)Grade 1 corneal staining was observed in some subjects at each visit. However, the staining was improved after lens cleaning, discontinuing lens wear, or applying artificial tears. No other adverse events were reported in all subjects during the 2a study. <p>CONCLUSION:Combining partial reduction Ortho-K and spectacles completely slowed myopic progression in high myopic adolescent after receiving the treatment for 1a, and partially reduced myopia progression after 2a of treatment. No severe ocular complications were found throughout the treatment. The combination treatment appeared to be effective and safe, but its long-term effect needs to be further assessed.http://ies.ijo.cn/cn_publish/2015/1/201501037.pdforthokeratologyhigh myopiamyopia control
spellingShingle Ming Luo
Sheng-Sheng Ma
Hong-Yang Li
Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
Guoji Yanke Zazhi
orthokeratology
high myopia
myopia control
title Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
title_full Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
title_fullStr Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
title_full_unstemmed Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
title_short Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
title_sort clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
topic orthokeratology
high myopia
myopia control
url http://ies.ijo.cn/cn_publish/2015/1/201501037.pdf
work_keys_str_mv AT mingluo clinicaleffectofpartialreductionorthokeratologyandspectaclesonhighmyopiaadolescents
AT shengshengma clinicaleffectofpartialreductionorthokeratologyandspectaclesonhighmyopiaadolescents
AT hongyangli clinicaleffectofpartialreductionorthokeratologyandspectaclesonhighmyopiaadolescents