Characterization of Permeability Barrier Dysfunction in a Murine Model of Cutaneous Field Cancerization Following Chronic UV-B Irradiation: Implications for the Pathogenesis of Skin Cancer

Characterization of Permeability Barrier Dysfunction in a Murine Model of Cutaneous Field Cancerization Following Chronic UV-B Irradiation: Implications for the Pathogenesis of Skin Cancer

Chronic ultraviolet B (UV-B) irradiation is known to be one of the most important hazards acting on the skin and poses a risk of developing photoaging, skin with cutaneous field cancerization (CFC), actinic keratosis (AKs), and squamous cell carcinomas (SCCs). Most of the UV-B light is absorbed in t...

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Bibliographic Details
Main Authors: Juan Luis Santiago, Jose Ramon Muñoz-Rodriguez, Miguel Angel de la Cruz-Morcillo, Clara Villar-Rodriguez, Lucia Gonzalez-Lopez, Carolina Aguado, Miriam Nuncia-Cantarero, Francisco Javier Redondo-Calvo, Jose Manuel Perez-Ortiz, Eva Maria Galan-Moya
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
cutaneous field cancerization
skin cancer
actinic keratosis
UV radiation
permeability barrier
epidermis
Online Access:https://www.mdpi.com/2072-6694/13/16/3935

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