Providing Biological Plausibility for Exposure–Health Relationships for the Mycotoxins Deoxynivalenol (DON) and Fumonisin B1 (FB1) in Humans Using the AOP Framework

Providing Biological Plausibility for Exposure–Health Relationships for the Mycotoxins Deoxynivalenol (DON) and Fumonisin B1 (FB1) in Humans Using the AOP Framework

Humans are chronically exposed to the mycotoxins deoxynivalenol (DON) and fumonisin B1 (FB1), as indicated by their widespread presence in foods and occasional exposure in the workplace. This exposure is confirmed by human biomonitoring (HBM) studies on (metabolites of) these mycotoxins in human mat...

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Bibliographic Details
Main Authors: Annick D. van den Brand, Lola Bajard, Inger-Lise Steffensen, Anne Lise Brantsæter, Hubert A. A. M. Dirven, Jochem Louisse, Ad Peijnenburg, Sophie Ndaw, Alberto Mantovani, Barbara De Santis, Marcel J. B. Mengelers
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Toxins
Subjects:
AOP: adverse outcome pathway
HBM: human biomonitoring
HBM4EU
human biomonitoring for Europe
DON: deoxynivalenol
FB1: fumonisin B1
Online Access:https://www.mdpi.com/2072-6651/14/4/279

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