Biologically derived epicardial patch induces macrophage mediated pathophysiologic repair in chronically infarcted swine hearts

Biologically derived epicardial patch induces macrophage mediated pathophysiologic repair in chronically infarcted swine hearts

Abstract There are nearly 65 million people with chronic heart failure (CHF) globally, with no treatment directed at the pathologic cause of the disease, the loss of functioning cardiomyocytes. We have an allogeneic cardiac patch comprised of cardiomyocytes and human fibroblasts on a bioresorbable m...

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Main Authors: J. J. Lancaster, A. Grijalva, J. Fink, J. Ref, S. Daugherty, S. Whitman, K. Fox, G. Gorman, L. D. Lancaster, R. Avery, T. Acharya, A. McArthur, J. Strom, M. K. Pierce, T. Moukabary, M. Borgstrom, D. Benson, M. Mangiola, A. C. Pandey, M. R. Zile, A. Bradshaw, J. W. Koevary, S. Goldman
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05564-w

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