The effect of ACACB cis-variants on gene expression and metabolic traits.

The effect of ACACB cis-variants on gene expression and metabolic traits.

Acetyl Coenzyme A carboxylase β (ACACB) is the rate-limiting enzyme in fatty acid oxidation, and continuous fatty acid oxidation in Acacb knock-out mice increases insulin sensitivity. Systematic human studies have not been performed to evaluate whether ACACB variants regulate gene expression and ins...

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Main Authors: Lijun Ma, Ashis K Mondal, Mariana Murea, Neeraj K Sharma, Anke Tönjes, Kurt A Langberg, Swapan K Das, Paul W Franks, Peter Kovacs, Peter A Antinozzi, Michael Stumvoll, John S Parks, Steven C Elbein, Barry I Freedman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3162605?pdf=render

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