Chronic Cadmium Exposure Alters Cardiac Matrix Metalloproteinases in the Heart of Sprague-Dawley Rat

Chronic Cadmium Exposure Alters Cardiac Matrix Metalloproteinases in the Heart of Sprague-Dawley Rat

The aim of this study was to evaluate the role of chronic cadmium exposure in modulating cardiac matrix metalloproteinases (MMPs) in the heart of rats. Adult male Sprague-Dawley rats were exposed to 15 ppm CdCl2 in drinking water for 10 weeks followed by withdrawal of cadmium treatment for 4 weeks....

Full description

Bibliographic Details
Main Authors:	Sandra Concepcion Das, Kavitha Varadharajan, Muralitharan Shanmugakonar, Hamda A. Al-Naemi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Series:	Frontiers in Pharmacology
Subjects:	cadmium cardiac inflammatory cytokines MMP TIMP
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.663048/full

Similar Items

White adipose tissue as a target for cadmium toxicity
by: Sarra Mohammed Attia, et al.
Published: (2022-10-01)

Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer
by: Irena Ivković, et al.
Published: (2022-12-01)

Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Prostate Cancer Progression
by: Yixuan Gong, et al.
Published: (2014-06-01)

Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Endometriosis Menstrual Blood
by: Tita Husnitawati Madjid, et al.
Published: (2020-06-01)

The Effect of Thiamine, Ascorbic Acid, and the Combination of Them on the Levels of Matrix Metalloproteinase-9 (MMP-9) and Tissue Inhibitor of Matrix Metalloproteinase-1 (TIMP-1) in Sepsis Patients
by: Lubis B, et al.
Published: (2022-09-01)

Interplay between matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in acute asthma exacerbation and airway remodeling
by: Ghada Mahmoud Mohamed, et al.
Published: (2012-07-01)

Immunohistochemical characterization of the expression of matrix metalloproteinase - 9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in the invasive endometrioid endometrial carcinoma
by: A. V. Chepets
Published: (2015-12-01)

Current Perspectives on the Role of Matrix Metalloproteinases in the Pathogenesis of Basal Cell Carcinoma
by: Mircea Tampa, et al.
Published: (2021-06-01)

Matrix Metalloproteinases MMP-2 and MMP-9, Their Inhibitors TIMP-1 and TIMP-2, Vascular Endothelial Growth Factor and sVEGFR-2 as Predictive Markers of Ischemic Retinopathy in Patients with Systemic Sclerosis—Case Series Report
by: Arleta Waszczykowska, et al.
Published: (2020-11-01)

SERUM CONCENTRATIONS OF MATRIX METALLOPROTEINASE-9, -13 AND TIMP-1 IN AN OVARIECTOMIZED WISTAR RAT MODEL OF OSTEOPOROSIS
by: Armine V. Grigoryan, et al.
Published: (2017-12-01)

Circulating matrix metalloproteinase MMP-9 and MMP-2/TIMP-2 complex are associated with spontaneous early pregnancy failure
by: Nissi Ritva, et al.
Published: (2013-01-01)

Study of the level of sputum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor metalloproteinase-1 (TIMP-1) in COPD patients
by: Sherif A. Esa, et al.
Published: (2014-10-01)

Insights into the Role of Matrix Metalloproteinases in Precancerous Conditions and in Colorectal Cancer
by: Zahra Pezeshkian, et al.
Published: (2021-12-01)

Expression of matrix metalloproteinases (MMP-1, MMP-2 and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in oral submucous fibrosis
by: Rajendran R, et al.
Published: (2006-01-01)

Expression of Matrix Metalloproteinases and Their Inhibitors in Squamous Cell Carcinoma of the Tonsil and Their Clinical Significance
by: Sei Young Lee, et al.
Published: (2011-06-01)

Changes in Gene and Protein Expression of Metalloproteinase-2 and -9 and Their Inhibitors TIMP2 and TIMP3 in Different Parts of Fluoride-Exposed Rat Brain
by: Agnieszka Łukomska, et al.
Published: (2020-12-01)

Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients
by: Yu-Feng Hsiao, et al.
Published: (2016-12-01)

Metalloproteinases in Endometrial Cancer—Are They Worth Measuring?
by: Kaja Michalczyk, et al.
Published: (2021-11-01)

Activity of genes of matrix metalloproteinases and their inhibitors in the Ligamentum flavum of patients with stenosing processes in spinal canal and dural sac
by: L. V. Rodionova, et al.
Published: (2021-12-01)

Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Metabolism: Insights into Health and Disease
by: Sébastien Molière, et al.
Published: (2023-06-01)

Urine Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Children with Type 1 Diabetes Mellitus
by: Zeynep Yürük Yıldırım, et al.
Published: (2019-06-01)

GENDER-RELATED DIFFERENCE IN AQUEOUS HUMOR MATRIX METALLOPROTEINASES MMP-2 AND TISSUE INHIBITOR OF MATRIX METALLOPROTEINASES IN PATIENTS WITH PSEUDOEXFOLIATION SYNDROME/GLAUCOMA
by: Gordana Zlatanović, et al.
Published: (2010-03-01)

Protection against periodontal destruction in diabetic condition with Sardinella longiceps fish oil: expression of matrix-metalloproteinase 8 and tissue inhibitor of metalloproteinase 1
by: Dian Widya Damaiyanti, et al.
Published: (2019-03-01)

Differential Spatio-Temporal Regulation of MMPs in the 5xFAD Mouse Model of Alzheimer’s disease: Evidence for aPro-Amyloidogenic Role of MT1-MMP
by: Nathalie ePy, et al.
Published: (2014-09-01)

Expression of matrix metalloproteinases (MMPs)−2/-7/-9/-14 and tissue inhibitors of MMPs (TIMPs)−1/-2 in bovine cutaneous fibropapillomas associated with BPV-2 infection
by: Florentina Daraban Bocaneti, et al.
Published: (2022-11-01)

Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer
by: Maciej Szmitkowski, et al.
Published: (2011-04-01)

LONG-TERM TREATMENT RESULTS OF BONE SARCOMA PATIENTS WITH CONSIDERATION OF SERUM METALLOPROTEINASE LEVELS
by: I. V. Babkina, et al.
Published: (2016-02-01)

Spinal matrix metalloproteinase 8 regulates pain after peripheral trauma
by: Tajerian M, et al.
Published: (2019-04-01)

Investigation of the relationship between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase with SARS CoV-2 infections
by: May K. Ismael, et al.
Published: (2023-04-01)

Effect of the p38 MAPK Inhibitor on the Expression of Metalloproteinases and Their Inhibitors during the Formation of Abdominal Adhesions
by: Irina A. Shurygina, et al.
Published: (2021-12-01)

Immunohistochemical characteristics of MMP-9 and TIMP-1 markers expression in the cerebral cortex in diabetes mellitus type 2
by: V. O. Shavrin, et al.
Published: (2020-08-01)

TIMP way to stop metastasis?
by: Katarzyna Jarosz, et al.
Published: (2017-08-01)

TIMP way to stop metastasis?
by: Katarzyna Jarosz, et al.
Published: (2017-08-01)

THE ROLE OF MATRIX METALLOPROTEINASE MMP-9, ITS INHIBITOR TIMP-1 AND INTERLEUKINE-1β IN PATHOGENESIS OF TRAUMATIC BRAIN INJURY
by: S. V. Ziablitsev, et al.
Published: (2016-09-01)

THE ROLE OF MATRIX METALLOPROTEINASE MMP-9, ITS INHIBITOR TIMP-1 AND INTERLEUKINE-1β IN PATHOGENESIS OF TRAUMATIC BRAIN INJURY
by: S. V. Ziablitsev, et al.
Published: (2016-09-01)

Effects of Curcumin against Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor Metalloproteinase-2 (TIMP-2) Serum Level on Rat Model of Liver Fibrosis Resolution Process
by: Supriono, et al.
Published: (2018-04-01)

Imbalance in extracellular matrix degradation in urethral stricture
by: Prihadi JC, et al.
Published: (2018-11-01)

Study the level of sputum matrix metalloproteinase-9 and tissue inhibitor metaloprotienase-1 in patients with interstitial lung diseases
by: Sherif A. Esa, et al.
Published: (2016-01-01)

The increased of MMP-9 and MMP-2 with the decreased of TIMP-1 on the uterosacral ligament after childbirth
by: Rahajeng Rahajeng
Published: (2018-08-01)

Structure and Function of Human Matrix Metalloproteinases
by: Helena Laronha, et al.
Published: (2020-04-01)