CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS

Gallstones are commonly related to the super-saturation of bile with cholesterol in the presence of nucleating agents. Clinical evidence show that gallstones are frequent in healthy persons with complex cystic ducts geometry, an indication that fluid mechanics of the bile flow may play a role in the...

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Main Authors: MUSHTAK AL-ATABI, S.B. CHIN, X.Y. LUO
Format: Article
Language:English
Published: Taylor's University 2006-06-01
Series:Journal of Engineering Science and Technology
Subjects:
Online Access:http://jestec.taylors.edu.my/Issue%201%20Vol%201%20June%2006/p01-09.pdf
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author MUSHTAK AL-ATABI
S.B. CHIN
X.Y. LUO
author_facet MUSHTAK AL-ATABI
S.B. CHIN
X.Y. LUO
author_sort MUSHTAK AL-ATABI
collection DOAJ
description Gallstones are commonly related to the super-saturation of bile with cholesterol in the presence of nucleating agents. Clinical evidence show that gallstones are frequent in healthy persons with complex cystic ducts geometry, an indication that fluid mechanics of the bile flow may play a role in the formation of gallstones. In order to evaluate this role, correlations between idealized cystic duct geometry and the pressure drop across it have been determined both experimentally and numerically simulated with Computational Fluid Dynamics (CFD) technique. This work presented here forms part of a larger project to understand the functions of the human cystic duct, especially the influence of its various anatomical structures on the resistance to bile flow, to provide insight into the pathogenesis of gallstone formation and the origins of biliary pain. This eventually will lead to the development of a vision based risk factors system to aid the medical consultants to assess the likelihood of a person developing gallstone.
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spelling doaj.art-fa7bda76415d4ce692436b73dc55ff502022-12-21T18:31:45ZengTaylor's UniversityJournal of Engineering Science and Technology1823-46902006-06-011119CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORSMUSHTAK AL-ATABIS.B. CHINX.Y. LUOGallstones are commonly related to the super-saturation of bile with cholesterol in the presence of nucleating agents. Clinical evidence show that gallstones are frequent in healthy persons with complex cystic ducts geometry, an indication that fluid mechanics of the bile flow may play a role in the formation of gallstones. In order to evaluate this role, correlations between idealized cystic duct geometry and the pressure drop across it have been determined both experimentally and numerically simulated with Computational Fluid Dynamics (CFD) technique. This work presented here forms part of a larger project to understand the functions of the human cystic duct, especially the influence of its various anatomical structures on the resistance to bile flow, to provide insight into the pathogenesis of gallstone formation and the origins of biliary pain. This eventually will lead to the development of a vision based risk factors system to aid the medical consultants to assess the likelihood of a person developing gallstone.http://jestec.taylors.edu.my/Issue%201%20Vol%201%20June%2006/p01-09.pdfGallstonesCystic ductSimulationsCFDSmart systems
spellingShingle MUSHTAK AL-ATABI
S.B. CHIN
X.Y. LUO
CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS
Journal of Engineering Science and Technology
Gallstones
Cystic duct
Simulations
CFD
Smart systems
title CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS
title_full CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS
title_fullStr CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS
title_full_unstemmed CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS
title_short CYSTIC DUCT VISUAL-BASED EVALUATION OF GALLSTONES FORMATION RISK FACTORS
title_sort cystic duct visual based evaluation of gallstones formation risk factors
topic Gallstones
Cystic duct
Simulations
CFD
Smart systems
url http://jestec.taylors.edu.my/Issue%201%20Vol%201%20June%2006/p01-09.pdf
work_keys_str_mv AT mushtakalatabi cysticductvisualbasedevaluationofgallstonesformationriskfactors
AT sbchin cysticductvisualbasedevaluationofgallstonesformationriskfactors
AT xyluo cysticductvisualbasedevaluationofgallstonesformationriskfactors