Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions
The complete conformational cycle of RNA translocation by Prp43 is revealed in atomic detail from molecular dynamics simulations.
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04751-z |
| _version_ | 1797849938627919872 |
|---|---|
| author | Robert A. Becker Jochen S. Hub |
| author_facet | Robert A. Becker Jochen S. Hub |
| author_sort | Robert A. Becker |
| collection | DOAJ |
| description | The complete conformational cycle of RNA translocation by Prp43 is revealed in atomic detail from molecular dynamics simulations. |
| first_indexed | 2024-04-09T18:52:17Z |
| format | Article |
| id | doaj.art-fa7c2e2d2da6496e91751cfd60280a83 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T18:52:17Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-fa7c2e2d2da6496e91751cfd60280a832023-04-09T11:24:39ZengNature PortfolioCommunications Biology2399-36422023-04-016111310.1038/s42003-023-04751-zContinuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitionsRobert A. Becker0Jochen S. Hub1Theoretical Physics and Center for Biophysics, Saarland UniversityTheoretical Physics and Center for Biophysics, Saarland UniversityThe complete conformational cycle of RNA translocation by Prp43 is revealed in atomic detail from molecular dynamics simulations.https://doi.org/10.1038/s42003-023-04751-z |
| spellingShingle | Robert A. Becker Jochen S. Hub Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions Communications Biology |
| title | Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions |
| title_full | Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions |
| title_fullStr | Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions |
| title_full_unstemmed | Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions |
| title_short | Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions |
| title_sort | continuous millisecond conformational cycle of a deah box helicase reveals control of domain motions by atomic scale transitions |
| url | https://doi.org/10.1038/s42003-023-04751-z |
| work_keys_str_mv | AT robertabecker continuousmillisecondconformationalcycleofadeahboxhelicaserevealscontrolofdomainmotionsbyatomicscaletransitions AT jochenshub continuousmillisecondconformationalcycleofadeahboxhelicaserevealscontrolofdomainmotionsbyatomicscaletransitions |