Exosomes from tubular epithelial cells undergoing epithelial‐to‐mesenchymal transition promote renal fibrosis by M1 macrophage activation

Abstract Kidney fibrosis is the common final pathway of chronic kidney disease (CKD), and it is distinguished by inflammation, mesenchymal transition with myofibroblast formation, and epithelial‐to‐mesenchymal transition (EMT). Macrophages are protuberant inflammatory cells in the kidney, and their...

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Bibliographic Details
Main Authors: Yuqing Lu, Rui Zhang, Xiameng Gu, Xuerong Wang, Peipei Xi, Xiaolan Chen
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2022-00080