RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

The strong familiality of living to extreme ages suggests that human longevity is genetically regulated. The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. There are likely many more genetic modifiers of huma...

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Bibliographic Details
Main Authors: Paola Sebastiani, Monty Montano, Annibale Puca, Nadia Solovieff, Toshio Kojima, Meng C Wang, Efthymia Melista, Micah Meltzer, Sylvia E J Fischer, Stacy Andersen, Stephen H Hartley, Amanda Sedgewick, Yasumichi Arai, Aviv Bergman, Nir Barzilai, Dellara F Terry, Alberto Riva, Chiara Viviani Anselmi, Alberto Malovini, Aya Kitamoto, Motoji Sawabe, Tomio Arai, Yasuyuki Gondo, Martin H Steinberg, Nobuyoshi Hirose, Gil Atzmon, Gary Ruvkun, Clinton T Baldwin, Thomas T Perls
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2788130?pdf=render

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