Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting
Introduction: An effective postoperative pain management is of utmost importance following cardiac surgery. Various agents, routes and modes are available for the treatment of postoperative pain. Subcutaneous route of administration is an easy and effective method of postoperative analgesia with...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2020-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/13837/44277_CE[Ra1]_F(SHU)_PF1(Su_AKA_KM)_PN(SL).pdf |
| _version_ | 1818389026935144448 |
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| author | CN Namitha Manjunath R Kamath Ananda Bange M Gopala Krishnan B Amith Kiran |
| author_facet | CN Namitha Manjunath R Kamath Ananda Bange M Gopala Krishnan B Amith Kiran |
| author_sort | CN Namitha |
| collection | DOAJ |
| description | Introduction: An effective postoperative pain management
is of utmost importance following cardiac surgery. Various
agents, routes and modes are available for the treatment of
postoperative pain. Subcutaneous route of administration is
an easy and effective method of postoperative analgesia with
improved patient satisfaction and lesser side effects compared
to intravenous route.
Aim: To evaluate the efficacy of Subcutaneous Morphine (SCM)
as postoperative analgesia following Coronary Artery Bypass
Grafting (CABG).
Materials and Methods: This study was designed as a
retrospective analytical survey from June 2015 to June 2017.
Medical records of all patients over 18 years of age who
underwent coronary artery bypass grafting were reviewed.
Patients belonging to ASA PS I, II and III, patients above
18 years of age and those posted for coronary artery bypass
grafting were included in the study. Patients were divided
into two groups: SCM group and Paracetamol (PCT) group,
depending on the primary analgesia they received. The two
groups were compared using Student’s t-test for normally
distributed continuous data or non-parametric tests if the data
were not normally distributed. Categorical data were compared
by Fisher’s-exact test. The p-values <0.05 were considered
statistically significant.
Results: A total of 102 records were reviewed, out of which
49 patients received SCM and 53 patients had received PCT as
their primary postoperative analgesia. It was observed that PCT
group required more additional analgesia (intravenous fentanyl/
tramadol) than SCM group which was statistically significant with
p-value of <0.001 and the duration of Cardiac Intensive Care
Unit (CICU) stay was more in PCT group with p-value of 0.001.
Postoperative side effects were significantly more in PCT group.
Conclusion: SCM can be effectively administered intermittently
for postoperative analgesia following CABG with similar
haemodynamic stability and minimal side effects as compared
to intermittent intravenous PCT. |
| first_indexed | 2024-12-14T04:35:12Z |
| format | Article |
| id | doaj.art-fa810c079e0f4668b365877a05553233 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-14T04:35:12Z |
| publishDate | 2020-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-fa810c079e0f4668b365877a055532332022-12-21T23:16:59ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-07-01147010310.7860/JCDR/2020/44277.13837Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass GraftingCN Namitha0Manjunath R Kamath1Ananda Bange2M Gopala Krishnan3B Amith Kiran4Assistant Professor, Department of Anaesthesiology, Eastpoint College of Medical Sciences and Research Centre, Bengaluru, Karnataka, India.Professor, Department of Anaesthesiology, K S Hegde Medical Academy, Mangalore, Karnataka, India.Professor, Department of Anaesthesiology, K S Hegde Medical Academy, Mangalore, Karnataka, India.Professor, Department of CTVS, K S Hegde Medical Academy, Mangalore, Karnataka, IndiaAssociate Professor, Department of CTVS, K S Hegde Medical Academy, Mangalore, Karnataka, India.Introduction: An effective postoperative pain management is of utmost importance following cardiac surgery. Various agents, routes and modes are available for the treatment of postoperative pain. Subcutaneous route of administration is an easy and effective method of postoperative analgesia with improved patient satisfaction and lesser side effects compared to intravenous route. Aim: To evaluate the efficacy of Subcutaneous Morphine (SCM) as postoperative analgesia following Coronary Artery Bypass Grafting (CABG). Materials and Methods: This study was designed as a retrospective analytical survey from June 2015 to June 2017. Medical records of all patients over 18 years of age who underwent coronary artery bypass grafting were reviewed. Patients belonging to ASA PS I, II and III, patients above 18 years of age and those posted for coronary artery bypass grafting were included in the study. Patients were divided into two groups: SCM group and Paracetamol (PCT) group, depending on the primary analgesia they received. The two groups were compared using Student’s t-test for normally distributed continuous data or non-parametric tests if the data were not normally distributed. Categorical data were compared by Fisher’s-exact test. The p-values <0.05 were considered statistically significant. Results: A total of 102 records were reviewed, out of which 49 patients received SCM and 53 patients had received PCT as their primary postoperative analgesia. It was observed that PCT group required more additional analgesia (intravenous fentanyl/ tramadol) than SCM group which was statistically significant with p-value of <0.001 and the duration of Cardiac Intensive Care Unit (CICU) stay was more in PCT group with p-value of 0.001. Postoperative side effects were significantly more in PCT group. Conclusion: SCM can be effectively administered intermittently for postoperative analgesia following CABG with similar haemodynamic stability and minimal side effects as compared to intermittent intravenous PCT.https://jcdr.net/articles/PDF/13837/44277_CE[Ra1]_F(SHU)_PF1(Su_AKA_KM)_PN(SL).pdfheart bypass surgerymultimodal analgesiapostoperative painsubcutaneous injection |
| spellingShingle | CN Namitha Manjunath R Kamath Ananda Bange M Gopala Krishnan B Amith Kiran Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting Journal of Clinical and Diagnostic Research heart bypass surgery multimodal analgesia postoperative pain subcutaneous injection |
| title | Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting |
| title_full | Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting |
| title_fullStr | Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting |
| title_full_unstemmed | Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting |
| title_short | Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting |
| title_sort | intermittent subcutaneous morphine for postoperative analgesia following coronary artery bypass grafting |
| topic | heart bypass surgery multimodal analgesia postoperative pain subcutaneous injection |
| url | https://jcdr.net/articles/PDF/13837/44277_CE[Ra1]_F(SHU)_PF1(Su_AKA_KM)_PN(SL).pdf |
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