Mutation Profiles of eGFP-Tagged Small Ruminant Morbillivirus During 45 Serial Passages in Ribavirin-Treated Cells

Mutation Profiles of eGFP-Tagged Small Ruminant Morbillivirus During 45 Serial Passages in Ribavirin-Treated Cells

Small ruminant morbillivirus (SRMV), formerly known as peste-des-petits-ruminants virus, classified into the genus Morbillivirus in the family Paramyxoviridae. Its L protein functions as the RNA-dependent RNA polymerases (RdRp) during viral replication. Due to the absence of efficient proofreading a...

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Bibliographic Details
Main Authors: Fuxiao Liu, Yanli Zou, Lin Li, Chunju Liu, Xiaodong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Veterinary Science
Subjects:
rSRMV-eGFP
next-generation sequencing
single-nucleotide variation
mutation
L protein
high-fidelity
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.690204/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.690204/full

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