Changes in Intrinsic Antibiotic Susceptibility during a Long-Term Evolution Experiment with <named-content content-type="genus-species">Escherichia coli</named-content>

Changes in Intrinsic Antibiotic Susceptibility during a Long-Term Evolution Experiment with <named-content content-type="genus-species">Escherichia coli</named-content>

ABSTRACT High-level resistance often evolves when populations of bacteria are exposed to antibiotics, by either mutations or horizontally acquired genes. There is also variation in the intrinsic resistance levels of different bacterial strains and species that is not associated with any known histor...

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Bibliographic Details
Main Authors: Otmane Lamrabet, Mikaël Martin, Richard E. Lenski, Dominique Schneider
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
Escherichia coli
antibiotic resistance
evolution
mutation accumulation
pleiotropy
Online Access:https://journals.asm.org/doi/10.1128/mBio.00189-19

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