Stimulation of gastroduodenal HCO3- secretion by lubiprostone mediated by different prostaglandin EP receptor subtypes

Stimulation of gastroduodenal HCO3- secretion by lubiprostone mediated by different prostaglandin EP receptor subtypes

We examined the stimulatory effects of lubiprostone, a bicyclic fatty acid derived from prostaglandin E1 and a chloride channel type-2 opener (ClC-2), on HCO3- secretion in the rat stomach and duodenum, with a focus on the EP receptor subtypes involved in this action. Under urethane anesthesia, an e...

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Bibliographic Details
Main Authors: Koji Takeuchi, Shusaku Hayashi, Kikuko Amagase
Format: Article
Language:English
Published: Herzen State Pedagogical University of Russia 2020-06-01
Series:Интегративная физиология
Subjects:
lubiprostone
HCO3- secretion
prostaglandin EP receptor subtypes
stomach
duodenum
rat
Online Access:https://intphysiology.ru/index.php/main/article/view/27

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