Estimating dates of origin and end of COVID-19 epidemics

Estimating the date at which an epidemic started in a country and the date at which it can end depending on interventions intensity are important to guide public health responses. Both are potentially shaped by similar factors including stochasticity (due to small population sizes), superspreading e...

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Main Authors: Beneteau, Thomas, Elie, Baptiste, Sofonea, Mircea T., Alizon, Samuel
Format: Article
Language:English
Published: Peer Community In 2021-12-01
Series:Peer Community Journal
Online Access:https://peercommunityjournal.org/articles/10.24072/pcjournal.63/
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author Beneteau, Thomas
Elie, Baptiste
Sofonea, Mircea T.
Alizon, Samuel
author_facet Beneteau, Thomas
Elie, Baptiste
Sofonea, Mircea T.
Alizon, Samuel
author_sort Beneteau, Thomas
collection DOAJ
description Estimating the date at which an epidemic started in a country and the date at which it can end depending on interventions intensity are important to guide public health responses. Both are potentially shaped by similar factors including stochasticity (due to small population sizes), superspreading events, and memory effects (the fact that the occurrence of some events, e.g. recovering from an infection, depend on the past, e.g. the number of days since the infection). Focusing on COVID-19 epidemics, we develop and analyse mathematical models to explore how these three factors may affect early and final epidemic dynamics. Regarding the date of origin, we find limited effects on the mean estimates, but strong effects on their variances. Regarding the date of extinction following lockdown onset, mean values decrease with stochasticity or with the presence of superspreading events. These results underline the importance of accounting for heterogeneity in infection history and transmission patterns to accurately capture early and late epidemic dynamics.
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spelling doaj.art-fa854b88b8e546e0babd29691e0fa13e2023-10-24T14:38:24ZengPeer Community InPeer Community Journal2804-38712021-12-01110.24072/pcjournal.6310.24072/pcjournal.63Estimating dates of origin and end of COVID-19 epidemicsBeneteau, Thomas0https://orcid.org/0000-0003-4885-696XElie, Baptiste1https://orcid.org/0000-0002-3832-6650Sofonea, Mircea T.2https://orcid.org/0000-0002-4499-0435Alizon, Samuel3https://orcid.org/0000-0002-0779-9543MIVEGEC, Univ Montpellier, CNRS, IRD – Montpellier, FranceMIVEGEC, Univ Montpellier, CNRS, IRD – Montpellier, FranceMIVEGEC, Univ Montpellier, CNRS, IRD – Montpellier, FranceMIVEGEC, Univ Montpellier, CNRS, IRD – Montpellier, FranceEstimating the date at which an epidemic started in a country and the date at which it can end depending on interventions intensity are important to guide public health responses. Both are potentially shaped by similar factors including stochasticity (due to small population sizes), superspreading events, and memory effects (the fact that the occurrence of some events, e.g. recovering from an infection, depend on the past, e.g. the number of days since the infection). Focusing on COVID-19 epidemics, we develop and analyse mathematical models to explore how these three factors may affect early and final epidemic dynamics. Regarding the date of origin, we find limited effects on the mean estimates, but strong effects on their variances. Regarding the date of extinction following lockdown onset, mean values decrease with stochasticity or with the presence of superspreading events. These results underline the importance of accounting for heterogeneity in infection history and transmission patterns to accurately capture early and late epidemic dynamics.https://peercommunityjournal.org/articles/10.24072/pcjournal.63/
spellingShingle Beneteau, Thomas
Elie, Baptiste
Sofonea, Mircea T.
Alizon, Samuel
Estimating dates of origin and end of COVID-19 epidemics
Peer Community Journal
title Estimating dates of origin and end of COVID-19 epidemics
title_full Estimating dates of origin and end of COVID-19 epidemics
title_fullStr Estimating dates of origin and end of COVID-19 epidemics
title_full_unstemmed Estimating dates of origin and end of COVID-19 epidemics
title_short Estimating dates of origin and end of COVID-19 epidemics
title_sort estimating dates of origin and end of covid 19 epidemics
url https://peercommunityjournal.org/articles/10.24072/pcjournal.63/
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