Alzheimer’s disease biomarkers in cerebrospinal fluid are stable with the Elecsys immunoassay to most pre-analytical influencing factors except freezing at -80 °C

Alzheimer’s disease biomarkers in cerebrospinal fluid are stable with the Elecsys immunoassay to most pre-analytical influencing factors except freezing at -80 °C

Abstract Background Alzheimer´s disease is considered a neurodegenerative disease and is diagnosed by exclusion, while the detection of specific cerebrospinal fluid (CSF) biomarkers, namely amyloid-beta (Aβ) peptides Aβ1–42 (Aß42), phospho-tau (181P; P-tau), and total-tau (T-tau), has been shown to...

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Bibliographic Details
Main Authors: Franz Felix Konen, Hannah Benedictine Maier, Alexandra Neyazi, Stefan Bleich, Konstantin Neumann, Thomas Skripuletz
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Neurological Research and Practice
Subjects:
Alzheimer´s disease
Cerebrospinal fluid
Biomarker
Amyloid ß1–42
Phospho-tau
Total-tau
Online Access:https://doi.org/10.1186/s42466-023-00257-5

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