Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
Tariq Bhat,1 Mohammed Ahmed,2 Hassan Baydoun,2 Zahraa Ghandour,3 Alina Bhat,2 Donald McCord11Division of Cardiology, 2Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA; 3Department of Internal Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon...
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Format: | Article |
Language: | English |
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Dove Medical Press
2014-07-01
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Series: | Journal of Blood Medicine |
Online Access: | http://www.dovepress.com/acute-st-segment-elevation-myocardial-infarction-in-a-young-patient-wi-peer-reviewed-article-JBM |
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author | Bhat T Ahmed M Baydoun H Ghandour Z Bhat A McCord D |
author_facet | Bhat T Ahmed M Baydoun H Ghandour Z Bhat A McCord D |
author_sort | Bhat T |
collection | DOAJ |
description | Tariq Bhat,1 Mohammed Ahmed,2 Hassan Baydoun,2 Zahraa Ghandour,3 Alina Bhat,2 Donald McCord11Division of Cardiology, 2Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA; 3Department of Internal Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, LebanonAbstract: Essential thrombocythemia (ET) is a neoplastic proliferation of mature myeloid cells – in particular, megakaryocytes – leading to persistently elevated platelet count. Usual clinical presentation is related to an increase in the risk of hemorrhage and/or thrombosis. Management of ET consists of antiplatelet therapies – mainly aspirin and cytoreductive therapies. Coronary involvement in patients with ET is rare. The optimal treatment strategies for ET patients presenting with acute myocardial infarction remains unclear. Acute interventions like intracoronary thrombolytic therapy, angioplasty, and coronary-artery bypass grafting have been reported in such patients. However, several questions remain unanswered about the acute and long-term management of these patients. Herein, we report the case of a 47-year-old female who presented with acute myocardial infarction as the first clinical sign of ET, and also present the long-term follow-up of this patient.Keywords: STEMI, platelets, hypercoagulability, thrombosis, antiplatelets |
first_indexed | 2024-04-14T01:42:46Z |
format | Article |
id | doaj.art-fa8d88ffcf1c400f9040df413b54d748 |
institution | Directory Open Access Journal |
issn | 1179-2736 |
language | English |
last_indexed | 2024-04-14T01:42:46Z |
publishDate | 2014-07-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Journal of Blood Medicine |
spelling | doaj.art-fa8d88ffcf1c400f9040df413b54d7482022-12-22T02:19:40ZengDove Medical PressJournal of Blood Medicine1179-27362014-07-012014default12312717712Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up reportBhat TAhmed MBaydoun HGhandour ZBhat AMcCord DTariq Bhat,1 Mohammed Ahmed,2 Hassan Baydoun,2 Zahraa Ghandour,3 Alina Bhat,2 Donald McCord11Division of Cardiology, 2Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA; 3Department of Internal Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, LebanonAbstract: Essential thrombocythemia (ET) is a neoplastic proliferation of mature myeloid cells – in particular, megakaryocytes – leading to persistently elevated platelet count. Usual clinical presentation is related to an increase in the risk of hemorrhage and/or thrombosis. Management of ET consists of antiplatelet therapies – mainly aspirin and cytoreductive therapies. Coronary involvement in patients with ET is rare. The optimal treatment strategies for ET patients presenting with acute myocardial infarction remains unclear. Acute interventions like intracoronary thrombolytic therapy, angioplasty, and coronary-artery bypass grafting have been reported in such patients. However, several questions remain unanswered about the acute and long-term management of these patients. Herein, we report the case of a 47-year-old female who presented with acute myocardial infarction as the first clinical sign of ET, and also present the long-term follow-up of this patient.Keywords: STEMI, platelets, hypercoagulability, thrombosis, antiplateletshttp://www.dovepress.com/acute-st-segment-elevation-myocardial-infarction-in-a-young-patient-wi-peer-reviewed-article-JBM |
spellingShingle | Bhat T Ahmed M Baydoun H Ghandour Z Bhat A McCord D Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report Journal of Blood Medicine |
title | Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report |
title_full | Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report |
title_fullStr | Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report |
title_full_unstemmed | Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report |
title_short | Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report |
title_sort | acute st segment elevation myocardial infarction in a young patient with essential thrombocythemia a case with long term follow up report |
url | http://www.dovepress.com/acute-st-segment-elevation-myocardial-infarction-in-a-young-patient-wi-peer-reviewed-article-JBM |
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