Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report

Tariq Bhat,1 Mohammed Ahmed,2 Hassan Baydoun,2 Zahraa Ghandour,3 Alina Bhat,2 Donald McCord11Division of Cardiology, 2Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA; 3Department of Internal Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon...

Full description

Bibliographic Details
Main Authors: Bhat T, Ahmed M, Baydoun H, Ghandour Z, Bhat A, McCord D
Format: Article
Language:English
Published: Dove Medical Press 2014-07-01
Series:Journal of Blood Medicine
Online Access:http://www.dovepress.com/acute-st-segment-elevation-myocardial-infarction-in-a-young-patient-wi-peer-reviewed-article-JBM
_version_ 1817993729147928576
author Bhat T
Ahmed M
Baydoun H
Ghandour Z
Bhat A
McCord D
author_facet Bhat T
Ahmed M
Baydoun H
Ghandour Z
Bhat A
McCord D
author_sort Bhat T
collection DOAJ
description Tariq Bhat,1 Mohammed Ahmed,2 Hassan Baydoun,2 Zahraa Ghandour,3 Alina Bhat,2 Donald McCord11Division of Cardiology, 2Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA; 3Department of Internal Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, LebanonAbstract: Essential thrombocythemia (ET) is a neoplastic proliferation of mature myeloid cells – in particular, megakaryocytes – leading to persistently elevated platelet count. Usual clinical presentation is related to an increase in the risk of hemorrhage and/or thrombosis. Management of ET consists of antiplatelet therapies – mainly aspirin and cytoreductive therapies. Coronary involvement in patients with ET is rare. The optimal treatment strategies for ET patients presenting with acute myocardial infarction remains unclear. Acute interventions like intracoronary thrombolytic therapy, angioplasty, and coronary-artery bypass grafting have been reported in such patients. However, several questions remain unanswered about the acute and long-term management of these patients. Herein, we report the case of a 47-year-old female who presented with acute myocardial infarction as the first clinical sign of ET, and also present the long-term follow-up of this patient.Keywords: STEMI, platelets, hypercoagulability, thrombosis, antiplatelets
first_indexed 2024-04-14T01:42:46Z
format Article
id doaj.art-fa8d88ffcf1c400f9040df413b54d748
institution Directory Open Access Journal
issn 1179-2736
language English
last_indexed 2024-04-14T01:42:46Z
publishDate 2014-07-01
publisher Dove Medical Press
record_format Article
series Journal of Blood Medicine
spelling doaj.art-fa8d88ffcf1c400f9040df413b54d7482022-12-22T02:19:40ZengDove Medical PressJournal of Blood Medicine1179-27362014-07-012014default12312717712Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up reportBhat TAhmed MBaydoun HGhandour ZBhat AMcCord DTariq Bhat,1 Mohammed Ahmed,2 Hassan Baydoun,2 Zahraa Ghandour,3 Alina Bhat,2 Donald McCord11Division of Cardiology, 2Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA; 3Department of Internal Medicine, Faculty of Medical Sciences, Lebanese University, Beirut, LebanonAbstract: Essential thrombocythemia (ET) is a neoplastic proliferation of mature myeloid cells – in particular, megakaryocytes – leading to persistently elevated platelet count. Usual clinical presentation is related to an increase in the risk of hemorrhage and/or thrombosis. Management of ET consists of antiplatelet therapies – mainly aspirin and cytoreductive therapies. Coronary involvement in patients with ET is rare. The optimal treatment strategies for ET patients presenting with acute myocardial infarction remains unclear. Acute interventions like intracoronary thrombolytic therapy, angioplasty, and coronary-artery bypass grafting have been reported in such patients. However, several questions remain unanswered about the acute and long-term management of these patients. Herein, we report the case of a 47-year-old female who presented with acute myocardial infarction as the first clinical sign of ET, and also present the long-term follow-up of this patient.Keywords: STEMI, platelets, hypercoagulability, thrombosis, antiplateletshttp://www.dovepress.com/acute-st-segment-elevation-myocardial-infarction-in-a-young-patient-wi-peer-reviewed-article-JBM
spellingShingle Bhat T
Ahmed M
Baydoun H
Ghandour Z
Bhat A
McCord D
Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
Journal of Blood Medicine
title Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
title_full Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
title_fullStr Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
title_full_unstemmed Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
title_short Acute ST-segment elevation myocardial infarction in a young patient with essential thrombocythemia: a case with long-term follow-up report
title_sort acute st segment elevation myocardial infarction in a young patient with essential thrombocythemia a case with long term follow up report
url http://www.dovepress.com/acute-st-segment-elevation-myocardial-infarction-in-a-young-patient-wi-peer-reviewed-article-JBM
work_keys_str_mv AT bhatt acutestsegmentelevationmyocardialinfarctioninayoungpatientwithessentialthrombocythemiaacasewithlongtermfollowupreport
AT ahmedm acutestsegmentelevationmyocardialinfarctioninayoungpatientwithessentialthrombocythemiaacasewithlongtermfollowupreport
AT baydounh acutestsegmentelevationmyocardialinfarctioninayoungpatientwithessentialthrombocythemiaacasewithlongtermfollowupreport
AT ghandourz acutestsegmentelevationmyocardialinfarctioninayoungpatientwithessentialthrombocythemiaacasewithlongtermfollowupreport
AT bhata acutestsegmentelevationmyocardialinfarctioninayoungpatientwithessentialthrombocythemiaacasewithlongtermfollowupreport
AT mccordd acutestsegmentelevationmyocardialinfarctioninayoungpatientwithessentialthrombocythemiaacasewithlongtermfollowupreport