The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma
Objective:Incidental micropapillary carcinoma (IMC) is the most common variant of thyroid malignancies. There are unmet needs regarding the efficacy of nodule size in the prediction of the coexistence of IMC. We aimed to measure the effect of nodule size on the prediction of the coexistence of IMC.M...
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| Format: | Article |
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Galenos Yayinevi
2021-09-01
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| Series: | Bagcilar Medical Bulletin |
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http://behmedicalbulletin.org/archives/archive-detail/article-preview/the-performance-analysis-of-the-thyroid-nodule-siz/47682
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| author | Nadir Adnan Hacım Gülçin Ercan Yiğit Ülgen Talar Vartanoğlu Aktokmakyan Merve Tokoçin Serhat Meriç Marko Velimirovic Candaş Erçetin Ahmet Akbaş Yüksel Altınel |
| author_facet | Nadir Adnan Hacım Gülçin Ercan Yiğit Ülgen Talar Vartanoğlu Aktokmakyan Merve Tokoçin Serhat Meriç Marko Velimirovic Candaş Erçetin Ahmet Akbaş Yüksel Altınel |
| author_sort | Nadir Adnan Hacım |
| collection | DOAJ |
| description | Objective:Incidental micropapillary carcinoma (IMC) is the most common variant of thyroid malignancies. There are unmet needs regarding the efficacy of nodule size in the prediction of the coexistence of IMC. We aimed to measure the effect of nodule size on the prediction of the coexistence of IMC.Method:The data of 194 patients who underwent biopsy for fine-needle aspiration cytology and subsequent thyroidectomy in a research and training hospital between January 2017 and February 2020 were analyzed retrospectively. The patients were divided into three groups according to the sizes of thyroid nodules as 0-10 mm, 11-20 mm, and >20 mm. Logistic regression analysis was performed.Results:The patients with nodule size between 0 mm and 10 mm mostly showed hypothyroidism (51.0% vs. 28.8% vs. 41.8%) while patients with size between 11 mm and 20 mm mostly had euthyroidism (44.2% vs. 45.1% vs. 41.8%, p=0.0175). Both malignancy (51.9% vs. 49.0% vs. 42.9%, p=0.544) and IMC (65.4% vs. 51.0% vs. 56.0%, p=0.32) were observed more likely in patients with moderate size (11-20 mm). We found the following variables to be predictors for the coexistence of IMC: absence of halo [odds ratio (OR): 4.50, 95% confidence interval (CI): 1.61-14.71, p=0.007], and interestingly decrease in vascularity [OR: 0.33, 95% CI: 0.12-0.87, p=0.030], and total thyroidectomy, [OR: 4.55, 95% CI: 2.30- 9.56, p<0.001].Conclusion:With increased nodule size (>2 cm), we reported more IMC inside the thyroid gland. However, the nodule size has the low performance to be a predictor for the coexistence of IMC in the thyroid gland. |
| first_indexed | 2024-04-10T14:11:38Z |
| format | Article |
| id | doaj.art-fa8da8ef5b594da981ea655542d5f9c6 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-04-10T14:11:38Z |
| publishDate | 2021-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-fa8da8ef5b594da981ea655542d5f9c62023-02-15T16:09:43ZengGalenos YayineviBagcilar Medical Bulletin2547-94312021-09-016323424110.4274/BMB.galenos.2021.02.02213049054The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary CarcinomaNadir Adnan Hacım0Gülçin Ercan1Yiğit Ülgen2Talar Vartanoğlu Aktokmakyan3Merve Tokoçin4Serhat Meriç5Marko Velimirovic6Candaş Erçetin7Ahmet Akbaş8Yüksel Altınel9 University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of Pathology, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey Massachusetts General Hospital, Harvard Medical School, Department of Medicine, Boston, USA University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey Objective:Incidental micropapillary carcinoma (IMC) is the most common variant of thyroid malignancies. There are unmet needs regarding the efficacy of nodule size in the prediction of the coexistence of IMC. We aimed to measure the effect of nodule size on the prediction of the coexistence of IMC.Method:The data of 194 patients who underwent biopsy for fine-needle aspiration cytology and subsequent thyroidectomy in a research and training hospital between January 2017 and February 2020 were analyzed retrospectively. The patients were divided into three groups according to the sizes of thyroid nodules as 0-10 mm, 11-20 mm, and >20 mm. Logistic regression analysis was performed.Results:The patients with nodule size between 0 mm and 10 mm mostly showed hypothyroidism (51.0% vs. 28.8% vs. 41.8%) while patients with size between 11 mm and 20 mm mostly had euthyroidism (44.2% vs. 45.1% vs. 41.8%, p=0.0175). Both malignancy (51.9% vs. 49.0% vs. 42.9%, p=0.544) and IMC (65.4% vs. 51.0% vs. 56.0%, p=0.32) were observed more likely in patients with moderate size (11-20 mm). We found the following variables to be predictors for the coexistence of IMC: absence of halo [odds ratio (OR): 4.50, 95% confidence interval (CI): 1.61-14.71, p=0.007], and interestingly decrease in vascularity [OR: 0.33, 95% CI: 0.12-0.87, p=0.030], and total thyroidectomy, [OR: 4.55, 95% CI: 2.30- 9.56, p<0.001].Conclusion:With increased nodule size (>2 cm), we reported more IMC inside the thyroid gland. However, the nodule size has the low performance to be a predictor for the coexistence of IMC in the thyroid gland. http://behmedicalbulletin.org/archives/archive-detail/article-preview/the-performance-analysis-of-the-thyroid-nodule-siz/47682 malignancynodule sizethyroidectomy |
| spellingShingle | Nadir Adnan Hacım Gülçin Ercan Yiğit Ülgen Talar Vartanoğlu Aktokmakyan Merve Tokoçin Serhat Meriç Marko Velimirovic Candaş Erçetin Ahmet Akbaş Yüksel Altınel The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma Bagcilar Medical Bulletin malignancy nodule size thyroidectomy |
| title | The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma |
| title_full | The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma |
| title_fullStr | The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma |
| title_full_unstemmed | The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma |
| title_short | The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma |
| title_sort | performance analysis of the thyroid nodule size to predict the coexistence of micropapillary carcinoma |
| topic | malignancy nodule size thyroidectomy |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/the-performance-analysis-of-the-thyroid-nodule-siz/47682
|
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