Hierarchical Porous Carbon—PLLA and PLGA Hybrid Nanoparticles for Intranasal Delivery of Galantamine for Alzheimer’s Disease Therapy

Hierarchical Porous Carbon—PLLA and PLGA Hybrid Nanoparticles for Intranasal Delivery of Galantamine for Alzheimer’s Disease Therapy

In the present study, poly(l-lactic acid) (PLLA) and poly(lactide-<i>co</i>-glycolide) (PLGA) hybrid nanoparticles were developed for intranasal delivery of galantamine, a drug used in severe to moderate cases of Alzheimer&#8217;s disease. Galantamine (GAL) was adsorbed first in hier...

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Bibliographic Details
Main Authors: Stavroula G. Nanaki, Konstantinos Spyrou, Chryssa Bekiari, Pelagia Veneti, Turki N. Baroud, Niki Karouta, Ioannis Grivas, Georgios C. Papadopoulos, Dimitrios Gournis, Dimitrios N. Bikiaris
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
galantamine
alzheimer’s
poly(l-lactic acid)
poly(lactide-<i>co</i>-glycolide)
hierarchical porous carbon
nanoencapsulation
drug delivery
intranasal delivery
Online Access:https://www.mdpi.com/1999-4923/12/3/227

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https://www.mdpi.com/1999-4923/12/3/227

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