Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes
Abstract Background Tsetse flies (Diptera: Glossinidae) are the vectors of African trypanosomosis, the causal agent of sleeping sickness in humans and nagana in animals. Glossina fuscipes fuscipes is one of the most important tsetse vectors of sleeping sickness, particularly in Central Africa. Due t...
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| Format: | Article |
| Language: | English |
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BMC
2018-11-01
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| Series: | BMC Microbiology |
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| Online Access: | http://link.springer.com/article/10.1186/s12866-018-1276-7 |
| _version_ | 1818119815114522624 |
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| author | Güler Demirbas-Uzel Andrew G. Parker Marc J. B. Vreysen Robert L. Mach Jeremy Bouyer Peter Takac Adly M. M. Abd-Alla |
| author_facet | Güler Demirbas-Uzel Andrew G. Parker Marc J. B. Vreysen Robert L. Mach Jeremy Bouyer Peter Takac Adly M. M. Abd-Alla |
| author_sort | Güler Demirbas-Uzel |
| collection | DOAJ |
| description | Abstract Background Tsetse flies (Diptera: Glossinidae) are the vectors of African trypanosomosis, the causal agent of sleeping sickness in humans and nagana in animals. Glossina fuscipes fuscipes is one of the most important tsetse vectors of sleeping sickness, particularly in Central Africa. Due to the development of resistance of the trypanosomes to the commonly used trypanocidal drugs and the lack of effective vaccines, vector control approaches remain the most effective strategies for sustainable management of those diseases. The Sterile Insect Technique (SIT) is an effective, environment-friendly method for the management of tsetse flies in the context of area-wide integrated pest management programs (AW-IPM). This technique relies on the mass-production of the target insect, its sterilization with ionizing radiation and the release of sterile males in the target area where they will mate with wild females and induce sterility in the native population. It has been shown that Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) infection causes a decrease in fecundity and fertility hampering the maintenance of colonies of the tsetse fly G. pallidipes. This virus has also been detected in different species of tsetse files. In this study, we evaluated the impact of GpSGHV on the performance of a colony of the heterologous host G. f. fuscipes, including the flies’ productivity, mortality, survival, flight propensity and mating ability and insemination rates. Results Even though GpSGHV infection did not induce SGH symptoms, it significantly reduced all examined parameters, except adult flight propensity and insemination rate. Conclusion These results emphasize the important role of GpSGHV management strategy in the maintenance of G. f. fuscipes colonies and the urgent need to implement measures to avoid virus infection, to ensure the optimal mass production of this tsetse species for use in AW-IPM programs with an SIT component. |
| first_indexed | 2024-12-11T05:16:11Z |
| format | Article |
| id | doaj.art-fa9080ba4acd4b2786efcd7de1dc34df |
| institution | Directory Open Access Journal |
| issn | 1471-2180 |
| language | English |
| last_indexed | 2024-12-11T05:16:11Z |
| publishDate | 2018-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Microbiology |
| spelling | doaj.art-fa9080ba4acd4b2786efcd7de1dc34df2022-12-22T01:19:49ZengBMCBMC Microbiology1471-21802018-11-0118S124525610.1186/s12866-018-1276-7Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipesGüler Demirbas-Uzel0Andrew G. Parker1Marc J. B. Vreysen2Robert L. Mach3Jeremy Bouyer4Peter Takac5Adly M. M. Abd-Alla6Insect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food & Agriculture, International Atomic Energy Agency, Vienna International CentreInsect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food & Agriculture, International Atomic Energy Agency, Vienna International CentreInsect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food & Agriculture, International Atomic Energy Agency, Vienna International CentreInstitute of Chemical, Environmental and Biological Engineering, Research Area Biochemical Technology, Vienna University of TechnologyInsect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food & Agriculture, International Atomic Energy Agency, Vienna International CentreSection of Molecular and Applied Zoology, Institute of Zoology, Slovak Academy of SciencesInsect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food & Agriculture, International Atomic Energy Agency, Vienna International CentreAbstract Background Tsetse flies (Diptera: Glossinidae) are the vectors of African trypanosomosis, the causal agent of sleeping sickness in humans and nagana in animals. Glossina fuscipes fuscipes is one of the most important tsetse vectors of sleeping sickness, particularly in Central Africa. Due to the development of resistance of the trypanosomes to the commonly used trypanocidal drugs and the lack of effective vaccines, vector control approaches remain the most effective strategies for sustainable management of those diseases. The Sterile Insect Technique (SIT) is an effective, environment-friendly method for the management of tsetse flies in the context of area-wide integrated pest management programs (AW-IPM). This technique relies on the mass-production of the target insect, its sterilization with ionizing radiation and the release of sterile males in the target area where they will mate with wild females and induce sterility in the native population. It has been shown that Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) infection causes a decrease in fecundity and fertility hampering the maintenance of colonies of the tsetse fly G. pallidipes. This virus has also been detected in different species of tsetse files. In this study, we evaluated the impact of GpSGHV on the performance of a colony of the heterologous host G. f. fuscipes, including the flies’ productivity, mortality, survival, flight propensity and mating ability and insemination rates. Results Even though GpSGHV infection did not induce SGH symptoms, it significantly reduced all examined parameters, except adult flight propensity and insemination rate. Conclusion These results emphasize the important role of GpSGHV management strategy in the maintenance of G. f. fuscipes colonies and the urgent need to implement measures to avoid virus infection, to ensure the optimal mass production of this tsetse species for use in AW-IPM programs with an SIT component.http://link.springer.com/article/10.1186/s12866-018-1276-7GlossinidaeHytrosaviridaeLongevityInseminationMating abilityFlight propensity |
| spellingShingle | Güler Demirbas-Uzel Andrew G. Parker Marc J. B. Vreysen Robert L. Mach Jeremy Bouyer Peter Takac Adly M. M. Abd-Alla Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes BMC Microbiology Glossinidae Hytrosaviridae Longevity Insemination Mating ability Flight propensity |
| title | Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes |
| title_full | Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes |
| title_fullStr | Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes |
| title_full_unstemmed | Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes |
| title_short | Impact of Glossina pallidipes salivary gland hypertrophy virus (GpSGHV) on a heterologous tsetse fly host, Glossina fuscipes fuscipes |
| title_sort | impact of glossina pallidipes salivary gland hypertrophy virus gpsghv on a heterologous tsetse fly host glossina fuscipes fuscipes |
| topic | Glossinidae Hytrosaviridae Longevity Insemination Mating ability Flight propensity |
| url | http://link.springer.com/article/10.1186/s12866-018-1276-7 |
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