Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension
Background: Studies have reported that medication literacy had a positive effect on medication adherence in patients with hypertension. However, little is known about the mechanism underlying this relationship in patients with hypertension.Objective: The purpose of this study was to investigate the...
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| Format: | Article |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2020.569092/full |
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| author | Zhiying Shen Zhiying Shen Zhiying Shen Shuangjiao Shi Shuangjiao Shi Siqing Ding Siqing Ding Zhuqing Zhong Zhuqing Zhong |
| author_facet | Zhiying Shen Zhiying Shen Zhiying Shen Shuangjiao Shi Shuangjiao Shi Siqing Ding Siqing Ding Zhuqing Zhong Zhuqing Zhong |
| author_sort | Zhiying Shen |
| collection | DOAJ |
| description | Background: Studies have reported that medication literacy had a positive effect on medication adherence in patients with hypertension. However, little is known about the mechanism underlying this relationship in patients with hypertension.Objective: The purpose of this study was to investigate the mediating effect of self-efficacy between medication literacy and medication adherence.Methods: A total of 790 patients with hypertension were investigated using the Chinese Medication Literacy Scale for Hypertensive Patients (C-MLSHP), the Morisky Medication Adherence Scale-8 (MMAS-8) and the Medication Adherence Self-efficacy Scale-Revision (MASES-R). Hierarchical regression and the bootstrap approach were used to analyze the mediating effect of self-efficacy on the relationship between medication literacy and medication adherence.Results: A total of 60.9% of hypertensive patients were low adherent to their antihypertensive drug regimens. Self‐efficacy had a significant positive correlation with medication literacy (r= 0.408, p < 0.001) and medication adherence (r = 0.591, p < 0.001). Self-efficacy accounts for 28.7% of the total mediating effect on the relationship between medication literacy and adherence to antihypertensive regimens for hypertensive patients.Conclusion: More than half of the hypertensive patients in the study were low adherent to antihypertensive regimens. Self-efficacy had a partial significant mediating effect on the relationship between medication literacy and medication adherence. Therefore, it was suggested that hypertensive patients’ medication adherence might be improved and driven by increasing self-efficacy. Targeted interventions to improve patients’ self-efficacy should be developed and implemented. In addition, health care providers should also be aware of the importance of medication literacy assessment and promotion in patients with hypertension. |
| first_indexed | 2024-12-17T01:26:40Z |
| format | Article |
| id | doaj.art-fa909b4d496b4f16a4548efbf9784df5 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-17T01:26:40Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-fa909b4d496b4f16a4548efbf9784df52022-12-21T22:08:41ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-12-011110.3389/fphar.2020.569092569092Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With HypertensionZhiying Shen0Zhiying Shen1Zhiying Shen2Shuangjiao Shi3Shuangjiao Shi4Siqing Ding5Siqing Ding6Zhuqing Zhong7Zhuqing Zhong8Department of Hematology, Third Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Nursing, Third Xiangya Hospital, Central South University, Changsha, ChinaClinical Nursing Safety Management Reasearch Center of Central South University, Third Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Nursing, Third Xiangya Hospital, Central South University, Changsha, ChinaClinical Nursing Safety Management Reasearch Center of Central South University, Third Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Nursing, Third Xiangya Hospital, Central South University, Changsha, ChinaClinical Nursing Safety Management Reasearch Center of Central South University, Third Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Nursing, Third Xiangya Hospital, Central South University, Changsha, ChinaClinical Nursing Safety Management Reasearch Center of Central South University, Third Xiangya Hospital, Central South University, Changsha, ChinaBackground: Studies have reported that medication literacy had a positive effect on medication adherence in patients with hypertension. However, little is known about the mechanism underlying this relationship in patients with hypertension.Objective: The purpose of this study was to investigate the mediating effect of self-efficacy between medication literacy and medication adherence.Methods: A total of 790 patients with hypertension were investigated using the Chinese Medication Literacy Scale for Hypertensive Patients (C-MLSHP), the Morisky Medication Adherence Scale-8 (MMAS-8) and the Medication Adherence Self-efficacy Scale-Revision (MASES-R). Hierarchical regression and the bootstrap approach were used to analyze the mediating effect of self-efficacy on the relationship between medication literacy and medication adherence.Results: A total of 60.9% of hypertensive patients were low adherent to their antihypertensive drug regimens. Self‐efficacy had a significant positive correlation with medication literacy (r= 0.408, p < 0.001) and medication adherence (r = 0.591, p < 0.001). Self-efficacy accounts for 28.7% of the total mediating effect on the relationship between medication literacy and adherence to antihypertensive regimens for hypertensive patients.Conclusion: More than half of the hypertensive patients in the study were low adherent to antihypertensive regimens. Self-efficacy had a partial significant mediating effect on the relationship between medication literacy and medication adherence. Therefore, it was suggested that hypertensive patients’ medication adherence might be improved and driven by increasing self-efficacy. Targeted interventions to improve patients’ self-efficacy should be developed and implemented. In addition, health care providers should also be aware of the importance of medication literacy assessment and promotion in patients with hypertension.https://www.frontiersin.org/articles/10.3389/fphar.2020.569092/fullself-efficacymedication literacymedication adherencehypertensionmediating effect |
| spellingShingle | Zhiying Shen Zhiying Shen Zhiying Shen Shuangjiao Shi Shuangjiao Shi Siqing Ding Siqing Ding Zhuqing Zhong Zhuqing Zhong Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension Frontiers in Pharmacology self-efficacy medication literacy medication adherence hypertension mediating effect |
| title | Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension |
| title_full | Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension |
| title_fullStr | Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension |
| title_full_unstemmed | Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension |
| title_short | Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension |
| title_sort | mediating effect of self efficacy on the relationship between medication literacy and medication adherence among patients with hypertension |
| topic | self-efficacy medication literacy medication adherence hypertension mediating effect |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2020.569092/full |
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